Chemical modification of lignins: Towards biobased polymers

Lipid nanoparticles (SLN, NLC) in cosmetic and pharmaceutical dermal products.

The dietary consumption of grape and its products is associated with a lower incidence of degenerative diseases such as cardiovascular disease and certain types of cancers. Most recent interest has focused on the bioactive phenolic compounds in grape. Anthocyanins, flavanols, flavonols and resveratrol are the most important grape polyphenols because they possess many biological activities, such as antioxidant, cardioprotective, anticancer, anti-inflammation, antiaging and antimicrobial properties. This review summarizes current knowledge on the bioactivities of grape phenolics. The extraction, isolation and identification methods of polyphenols from grape as well as their bioavailability and potential toxicity also are included.

https://www.mdpi.com/1422-0067/11/2/622/pdf

Biological Activities of Polyphenols from Grapes

Towards lignin-based functional materials in a sustainable world

Value-adding to cellulosic ethanol: lignin polymers.

Comparative antioxidant and cytotoxic effects of lignins from different sources

Nanoparticles have received much attention recently due to their use in cancer therapy. Studies have shown that different metal oxide nanoparticles induce cytotoxicity in cancer cells, but not in normal cells. In some cases, such anticancer activity has been demonstrated to hold for the nanoparticle alone or in combination with different therapies, such as photocatalytic therapy or some anticancer drugs. Zinc oxide nanoparticles have been shown to have this activity alone or when loaded with an anticancer drug, such as doxorubicin. Other nanoparticles that show cytotoxic effects on cancer cells include cobalt oxide, iron oxide and copper oxide. The antitumor mechanism could work through the generation of reactive oxygen species or apoptosis and necrosis, among other possibilities. Here, we review the most significant antitumor results obtained with different metal oxide nanoparticles.

/pdf/antitumor-activities-of-metal-oxide-nanoparticles-4tgmhavjpu.pdf

Antitumor Activities of Metal Oxide Nanoparticles.

Potential applications of antioxidant lignins from different sources

https://onlinelibrary.wiley.com/doi/pdf/10.1002/jps.21088

Alternative methods for eye and skin irritation tests: an overview.

A review of the pharmacological applications of lignins provides evidence of their protective role against the development of different diseases. In many cases, the effects of lignins could be explained by their antioxidant capacity. Here, we present a systematic review of the literature from the period 2010–2016 which provides information concerning new applications of lignins derived from recent research. The most promising findings are reported, including the methodologies employed and results obtained with lignins or their derivatives which may improve human health. We highlight potential applications in the treatment of obesity, diabetes, thrombosis, viral infections and cancer. Moreover, we report both that lignins can be used in the preparation of nanoparticles to deliver different drugs and also their use in photoprotection.

/pdf/lignins-and-their-derivatives-with-beneficial-effects-on-1owj69dn9r.pdf

María Pilar Vinardell

Papers

Comparative antioxidant and cytotoxic effects of lignins from different sources

Antitumor Activities of Metal Oxide Nanoparticles.

Potential applications of antioxidant lignins from different sources

Alternative methods for eye and skin irritation tests: an overview.

Lignins and Their Derivatives with Beneficial Effects on Human Health.