M
Mariarosa Mazza
Researcher at University of Manchester
Publications - 24
Citations - 1347
Mariarosa Mazza is an academic researcher from University of Manchester. The author has contributed to research in topics: Nanomedicine & In vivo. The author has an hindex of 12, co-authored 23 publications receiving 1055 citations. Previous affiliations of Mariarosa Mazza include University College London & University of London.
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Journal ArticleDOI
Controlled In Vivo Swimming of a Swarm of Bacteria‐Like Microrobotic Flagella
Ania Servant,Ania Servant,Famin Qiu,Mariarosa Mazza,Mariarosa Mazza,Kostas Kostarelos,Kostas Kostarelos,Bradley J. Nelson +7 more
TL;DR: In vivo imaging and actuation of a swarm of magnetic helical microswimmers by external magnetic fields in deep tissue is demonstrated for the first time, yielding a generation of micrometer-scale transporters with numerous applications in biomedicine including synthetic biology, assisted fertilization, and drug/gene delivery.
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In Vivo Biomolecule Corona around Blood-Circulating, Clinically Used and Antibody-Targeted Lipid Bilayer Nanoscale Vesicles.
Marilena Hadjidemetriou,Zahraa S. Al-Ahmady,Mariarosa Mazza,Richard F. Collins,Kenneth A. Dawson,Kostas Kostarelos +5 more
TL;DR: Both in vitro and in vivo formed protein coronas were found to significantly reduce receptor binding and cellular internalization of antibody-conjugated liposomes; however, the in vivo corona formation did not lead to complete ablation of their targeting capability.
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Amphiphilic poly(l-amino acids) : New materials for drug delivery
TL;DR: Am Amphiphilic polymers based on amino acids are the subject of this review and have been employed as drug solubilisers, tumour targeting agents, gene delivery vectors and facilitators of intracellular drug uptake.
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The Human In Vivo Biomolecule Corona onto PEGylated Liposomes: A Proof-of-Concept Clinical Study
Marilena Hadjidemetriou,Sarah McAdam,Grace Garner,Chelsey Thackeray,David Knight,Duncan L. Smith,Zahraa S. Al-Ahmady,Mariarosa Mazza,Jane Rogan,Andrew R Clamp,Kostas Kostarelos +10 more
TL;DR: The previously elusive or postulated formation of protein corona around nanoparticles in vivo in humans is described and it is illustrated that it can potentially be used as a novel tool to analyze the blood circulation proteome.
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Liposome-gold nanorod hybrids for high-resolution visualization deep in tissues
Neus Lozano,Wafa' T Al-Jamal,Adrian Taruttis,Nicolas Beziere,Neal C. Burton,Jeroen Van den Bossche,Mariarosa Mazza,Eva Herzog,Vasilis Ntziachristos,Kostas Kostarelos +9 more
TL;DR: A self-assembled liposome-gold nanorod hybrid vesicular system that consists of lipid-bilayer-associated gold nanorods designed to allow deep tissue detection, therapy, and monitoring in living animals using multispectral optoacoustic tomography has been fabricated and characterized in vitro and in vivo.