M
Marina Della
Researcher at University of Cambridge
Publications - 3
Citations - 547
Marina Della is an academic researcher from University of Cambridge. The author has contributed to research in topics: DNA repair & DNA ligase. The author has an hindex of 2, co-authored 3 publications receiving 516 citations.
Papers
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Journal ArticleDOI
Identification of a DNA Nonhomologous End-Joining Complex in Bacteria
Geoffrey R. Weller,Boris Kysela,Rajat Roy,Louise M. Tonkin,Elizabeth Scanlan,Marina Della,Susanne Krogh Devine,Jonathan P. Day,Adam Wilkinson,Fabrizio d'Adda di Fagagna,Kevin M. Devine,Richard P. Bowater,Penny A. Jeggo,Stephen P. Jackson,Aidan J. Doherty +14 more
TL;DR: These data provide evidence that many bacteria possess a DNA DSB repair apparatus that shares many features with the NHEJ system of eukarya and suggest that this DNA repair pathway arose before the prokaryotic and eukaryotic lineages diverged.
Journal ArticleDOI
Mycobacterial Ku and Ligase Proteins Constitute a Two-Component NHEJ Repair Machine
Marina Della,Phillip L. Palmbos,Hui Min Tseng,Louise M. Tonkin,Louise M. Tonkin,James M. Daley,Leana M Topper,Robert S. Pitcher,Alan E. Tomkinson,Thomas E. Wilson,Aidan J. Doherty +10 more
TL;DR: It is demonstrated that prokaryotic Ku and ligase form a bona fide NHEJ system that encodes all the recognition, processing, and ligation activities required for DSB repair.
Patent
Prokaryotic dna repair ligases
TL;DR: In this paper, a prokaryotic DNA repair ligase was shown to possess a range of activities that allow the ligation and repair of non-compatible DNA ends and double strand breaks (DSBs).