M
Marina Zoppo
Researcher at University of Pisa
Publications - 9
Citations - 158
Marina Zoppo is an academic researcher from University of Pisa. The author has contributed to research in topics: Candida parapsilosis & Mutant. The author has an hindex of 6, co-authored 9 publications receiving 107 citations.
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Journal ArticleDOI
TbD1 deletion as a driver of the evolutionary success of modern epidemic Mycobacterium tuberculosis lineages.
Daria Bottai,Wafa Frigui,Fadel Sayes,Mariagrazia Di Luca,Dalila Spadoni,Alexandre Pawlik,Marina Zoppo,Mickael Orgeur,Varun Khanna,David Hardy,Sophie Mangenot,Valérie Barbe,Claudine Médigue,Laurence Ma,Christiane Bouchier,Arianna Tavanti,Gerald Larrouy-Maumus,Roland Brosch +17 more
TL;DR: It is shown that deletion of TbD1 correlates with enhanced Mtb virulence in animal models, mirroring the development of hypoxic granulomas in human disease progression.
Journal ArticleDOI
Targeted gene disruption in Candida parapsilosis demonstrates a role for CPAR2_404800 in adhesion to a biotic surface and in a murine model of ascending urinary tract infection
Alessia Bertini,Marina Zoppo,Lisa Lombardi,Cosmeri Rizzato,Elena De Carolis,Antonietta Vella,Riccardo Torelli,Maurizio Sanguinetti,Arianna Tavanti +8 more
TL;DR: Findings provide the first evidence for a direct role of CPAR2_404800 in C. parapsilosis adhesion to host surfaces and demonstrate its contribution to the pathogenesis of murine urinary candidiasis.
Journal ArticleDOI
CORT0C04210 is required for Candida orthopsilosis adhesion to human buccal cells.
Marina Zoppo,Lisa Lombardi,Cosmeri Rizzato,Antonella Lupetti,Daria Bottai,Csaba Papp,Attila Gácser,Arianna Tavanti +7 more
TL;DR: These findings provide the first evidence that CRISPR/Cas9 can be successfully used in C. orthopsilosis and demonstrate that CoALS4210 plays a direct role in the adhesion of C. Orthopsilotic edited strains to buccal cells.
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Characterization of the Candida orthopsilosis agglutinin-like sequence (ALS) genes.
Lisa Lombardi,Marina Zoppo,Cosmeri Rizzato,Daria Bottai,Alvaro G. Hernandez,Lois L. Hoyer,Arianna Tavanti +6 more
TL;DR: Overall, long-read DNA sequencing methodology was instrumental in generating an accurate assembly of CoALS genes, thus revealing their unconventional features and first insights into their allelic variability within C. orthopsilosis clinical isolates.
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CoERG11 A395T mutation confers azole resistance in Candida orthopsilosis clinical isolates
Cosmeri Rizzato,Noemi Poma,Marina Zoppo,Brunella Posteraro,Enrica Mello,Daria Bottai,Antonella Lupetti,Maurizio Sanguinetti,Arianna Tavanti +8 more
TL;DR: These findings provide the first evidence that the CoErg11 Y132F substitution confers multi-azole resistance in C. orthopsilosis.