M
Marion Sallée
Researcher at Aix-Marseille University
Publications - 48
Citations - 2061
Marion Sallée is an academic researcher from Aix-Marseille University. The author has contributed to research in topics: Kidney disease & Medicine. The author has an hindex of 15, co-authored 38 publications receiving 1511 citations. Previous affiliations of Marion Sallée include Institut national de la recherche agronomique & Necker-Enfants Malades Hospital.
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Journal ArticleDOI
Pregnancy-Associated Hemolytic Uremic Syndrome Revisited in the Era of Complement Gene Mutations
Fadi Fakhouri,Lubka T. Roumenina,François Provôt,Marion Sallée,Sophie Caillard,Lionel Couzi,Marie Essig,David Ribes,Marie-Agnès Dragon-Durey,Franck Bridoux,Eric Rondeau,Véronique Frémeaux-Bacchi +11 more
TL;DR: A retrospective study to assess the presentation and outcomes of patients presenting with P-aHUS and the prevalence of alternative C3 convertase dysregulation and better understanding of complement dysregulation in pregnancy complications is essential.
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Endothelium structure and function in kidney health and disease
Noémie Jourde-Chiche,Noémie Jourde-Chiche,Fadi Fakhouri,Laetitia Dou,Jeremy Bellien,Stéphane Burtey,Stéphane Burtey,Marie Frimat,Pierre-André Jarrot,Gilles Kaplanski,Moglie Le Quintrec,Vincent Pernin,Claire Rigothier,Marion Sallée,Marion Sallée,Véronique Frémeaux-Bacchi,Dominique Guerrot,Lubka T. Roumenina,Lubka T. Roumenina,Lubka T. Roumenina +19 more
TL;DR: Therapeutic strategies aimed at preserving and/or restoring the integrity of the endothelial glycocalyx, reversing the procoagulant and pro-inflammatory phenotype of injured endothelial cells and slowing renal fibrosis hold promise for the treatment of renal disease.
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The Cardiovascular Effect of the Uremic Solute Indole-3 Acetic Acid
Laetitia Dou,Marion Sallée,Claire Cerini,Stéphane Poitevin,Bertrand Gondouin,Noémie Jourde-Chiche,Karim Fallague,Philippe Brunet,Raymond Calaf,Bertrand Dussol,Bernard Mallet,Françoise Dignat-George,Stéphane Burtey +12 more
TL;DR: Serum IAA may be an independent predictor of mortality and cardiovascular events in patients with CKD and has prooxidant and proinflammatory effects in vitro and in cultured human endothelial cells.
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Indolic uremic solutes increase tissue factor production in endothelial cells by the aryl hydrocarbon receptor pathway.
Bertrand Gondouin,Claire Cerini,Laetitia Dou,Marion Sallée,A. Duval-Sabatier,Anneleen Pletinck,Raymond Calaf,Romaric Lacroix,Noémie Jourde-Chiche,Stéphane Poitevin,Laurent Arnaud,Raymond Vanholder,Philippe Brunet,Françoise Dignat-George,Stéphane Burtey +14 more
TL;DR: Indolic uremic solutes increase tissue factor production in endothelial and peripheral blood mononuclear cells by AHR activation, evoking a 'dioxin-like' effect, which may help understand the high cardiovascular risk of CKD patients.
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The Aryl Hydrocarbon Receptor-Activating Effect of Uremic Toxins from Tryptophan Metabolism: A New Concept to Understand Cardiovascular Complications of Chronic Kidney Disease
TL;DR: It is discussed here how the cardiovascular effects of these uremic toxins could be mediated by AhR activation, in a “dioxin-like” effect.