M
Marios Politis
Researcher at King's College London
Publications - 167
Citations - 9497
Marios Politis is an academic researcher from King's College London. The author has contributed to research in topics: Parkinson's disease & Serotonergic. The author has an hindex of 47, co-authored 158 publications receiving 7504 citations. Previous affiliations of Marios Politis include Hammersmith Hospital & King's College.
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Journal ArticleDOI
PET image reconstruction using multi-parametric anato-functional priors.
Abolfazl Mehranian,Martin A. Belzunce,Flavia Niccolini,Marios Politis,Claudia Prieto,Federico Turkheimer,Alexander Hammers,Andrew J. Reader +7 more
TL;DR: Results showed that the joint Burg entropy prior far outperformed the conventional anatomical priors in terms of preserving PET unique lesions, while still reconstructing functional boundaries with corresponding MR boundaries, and are therefore likely to increase the diagnostic confidence in MR-guided PET image reconstructions.
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Dyskinesias after neural transplantation in Parkinson's disease: what do we know and what is next?
TL;DR: The findings from this study showed serotonergic hyperinnervation in the grafted striatum of two patients with Parkinson's disease who exhibited major motor recovery after transplantation with fetal mesencephalic tissue but later developed graft-induced dyskinesias, which were significantly attenuated by administration of a serotonin agonist.
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Motor associations of iron accumulation in deep grey matter nuclei in Parkinson's disease: a cross-sectional study of iron-related magnetic resonance imaging susceptibility.
Antonio Martin-Bastida,Nicholas P. Lao-Kaim,Clare Loane,Clare Loane,Marios Politis,Marios Politis,Andreas-Antonios Roussakis,Natalie Valle-Guzman,Zinovia Kefalopoulou,Gesine Paul-Visse,Håkan Widner,Yue Xing,Stefan Schwarz,Dorothee P. Auer,Thomas Foltynie,Roger A. Barker,Roger A. Barker,Paola Piccini +17 more
TL;DR: To determine whether iron deposition in deep brain nuclei assessed using high‐pass filtered phase imaging plays a role in motor disease severity in Parkinson's disease, data are analyzed through positron emission tomography and electrophysiology.
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Aberrant nigral diffusion in Parkinson's disease : A longitudinal diffusion tensor imaging study
Clare Loane,Clare Loane,Clare Loane,Marios Politis,Marios Politis,Z Kefalopoulou,Natalie Valle-Guzman,Gesine Paul,Håkan Widner,Thomas Foltynie,Roger A. Barker,Paola Piccini +11 more
TL;DR: Measuring microstructure alterations with diffusion tensor imaging in PD is potentially a valuable tool to use as a biomarker for early diagnosis and to track disease progression.
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Neuroimaging in Lewy body dementia
TL;DR: An overview of neuroimaging applications in patients with DLB is provided and novel PET molecular imaging modalities, such as amyloid and tau imaging, may provide further insights into DLB pathophysiology and may aid in early diagnosis.