M
Mark B. Effron
Researcher at Eli Lilly and Company
Publications - 153
Citations - 8547
Mark B. Effron is an academic researcher from Eli Lilly and Company. The author has contributed to research in topics: Percutaneous coronary intervention & Prasugrel. The author has an hindex of 38, co-authored 138 publications receiving 8032 citations. Previous affiliations of Mark B. Effron include Northwestern University & Durham University.
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Journal Article
The effect of digoxin on mortality and morbidity in patients with heart failure
Gilbert J. Perry,Edward B. Brown,R Thornton,T Shiva,J Hubbard,K R Reddy,J E Doherty,F P Cardello,A Fast,Martha J. Radford,J S Folger,G Bhaskar,R G Zoble,Sridharan,R R Loungani,Mihai Gheorghiade,A Hsieh,Carl L. Tommaso,M Mansuri,M A Guess,S Akhtar,Stefan Wagner,K Hagan,K M McIntyre,P Ruble,M Moten,A Riley,Gordon L. Pierpont,Anand,G Patel,B S Puram,BR Eladasari,J Karnegis,E Gillie,M H Crawford,W F Graettinger,A Shah,J Sacco,M A Chaudhry,D Dolen,N ElSherif,S BekheitSaad,E E Campos,J G Greene,Khanijo,U Kumar,G I Mallis,S Mookherjee,M DibnerDunlap,S C Gupta,K Danisa,U Thadani,A Tan,M Rajachar,M Amidi,M V OReilly,C A Hassapoyannes,M L Davies,V A Kumar,D Okerson,K B Ramanathan,B Putatunda,A Gollapudi,A Montero,Panchanan Mohanty,Charles Y. Lui,S Thagirisa,R W Lee,T R Glatter,K Bodine,D K Roberts,M Bertoglio,G W Dennish,R J Sarma,Gabriel Gregoratos,D C Rausch,W A Pitt,B M Kennelly,D Fahrenholtz,R Gordon,L Horwitz,R Rothbart,P Nutting,L Lutz,D L Copen,Andrew Rashkow,J Babb,L VanVoorhees,A Silverman,M E Stillabower,A B Miller,H T NguyenPho,R E Safford,S Fishman,J C Neiman,M Stein,JC Dominguez,G T Abernathy,P H Nair,L S Goodman,T H Cook,W Wickemeyer,D M Berkson,James Mathew,H G Richman,D L Lubell,R M Lang,E J Zajac,R Rosenstein,Marc A. Silver,J G Shanes,K J Kelly,M H Pequignot,Robert B. Campbell,P C Kirlin,D B Ziperman,D M Denny,L Gamble,Matthew C. Weiss,P K Kaimal,R W Dhurandhar,H Ventura,M L Godley,C Pu,E C Schick,D J Barbour,D Salmon,M Goldstein,Mark B. Effron,Jerome L. Fleg,K L Baughman,R Weiss,Keith M. Marzilli Ericson,W A Sturrock,J Heinsimer,G C Timmis,Sidney C. Smith,D D Shrestha,Wfc Duvernoy,J Hickner,B K Lewis,T K OBrien,S A Yarows,H J Willens,D J Mast,Thomas H. Johnson,RJ Rodeheffer,M Siefert,L Swenson,P Denes,R Gudapati,F R Charles,Michael W. Rich,Beckham,W P Hamilton,PB Abele,DM Harper,R L OKelly,A D Forker,F R Kahl,B W Garrou,TE Klang,K Popio,S Mohiuddin,E M Pollak,A Chiaramida,J J Gregory,L A Papa,J Abrams,S Ung,C K Jutila,R P Croke,S Chiaramida,R Lucariello,Da Rim,Mark Goldberger,R M Kohn,S Graham,Edward F. Philbin,K Sheesley,A Nafziger,G Macina,J T Hsueh,S Zoneraich,A Binder,C Weinstein,J Morrison,A Cameron,E J Vanderbush,J Brown,P N Pande,E Lader,R Kay,D Bloomfield,T Costantino,D E Heiselman,S Radwany,Smith,R E Hobbs,T D Fraker,T R Frerking,A C DeLeon,L G Christie,M Toren,J Grover,F D McBarron,D E Harris,R W McLean,L Morris,J Zatuchni,J P Boehmer,B S Clemson,H Lipshutz,R S Small,R Ufret,JE LugoRodriquez,A H Khan,M Yousefian,G C Friesinger,D Ely,JA Farmer,J B Young,R M Payne,R E Fowles,A B Lee,Y Shalev,AlBitar,G S Schroeder,L Radant,T L Hankey,S Rezkalla,D L Groden,K K Teo,DP Humen,D Wong,P V Greenwood,T Talibi,W Hui,WP Klinke,Mpj Senaratne,M Goeres,D F Hughes,Mar Sayeed,D L Roth,Belenkie,D E Manyari,K Borgersen,L Read,D Kinloch,R Reid,N C Barber,B A Horner,G Kenefick,R A Kuritzky,Imrie,K R Wagner,Simon W. Rabkin,H F Mizgala,L Tarry,A Dodek,J M Kornder,T Ashton,D M Barr,J Dufton,R Sweeny,A Morris,R Bessoudo,D Marr,Milton,B Thompson,Robinson,Bruce Sussex,M Tobin,D P McMahon,D Folkins,R Crowell,LD Lalonde,C Koilpillai,R J Hatheway,MG OReilly,T Machel,Hack,J W Stewart,Paul H. Tanser,B Sullivan,S Hagar,B Quinn,RA Davies,M G Baird,W L Williams,M Lemay,L Higginson,M Turek,R A Sochowski,A Weeks,M H Jacobs,R Baigrie,M A DeVilla,G Vertes,B Bozek,J E Goode,A J Ricci,J Swan,D A Fell,S N LevinoffRoth,Jmo Arnold,L Patrick,R F Southern,C Rinne,D Brisbin,J P DeYoung,T Baitz,S Vizel,J Minkowitz,P Letarte,Y K Chan,K K Kwok,S Nawaz,F Ganjavi,L Yao,J Misterski,D L Raco,A R Hess,G Kuruvilla,L Silverberg,D Borts,J C Fulop,M Weingert,R P Carter,B M Sahay,J E Hickey,G Lalonde,G Gosselin,Martial G. Bourassa,C Goulet,M Joyal,M Methe,G Honos,David Fitchett,A Serpa,F Sestier,G Roberge,Y Latour,C Rondeau,D Gossard,Jhf Lenis,R Brossoit,L Simard,F Delage,P. Auger,D Saulnier,P Talbot,J Beaudoin,J Campeau,G Pruneau,M Tamilia,G Boutros,B Comeau,R Starra,R StHilaire,J Veilleux,M Mercier,J F Poulin,K MacLellan,S Lepage,Jean L. Rouleau,N Bruinsma,C Levesque,R DeLarochelliere,M LeBlanc,S Kouz,G S Kiwan,M Laforest,J Brooks,G Bouchard,P B Gervais,James M. Brophy,J Gagnon,N Habib,A K Basu,A T Lutterodt,M Khouri,R Gorlin,Debra Egan,Rekha Garg,Salim Yusuf,T Montague,T W Smith,Jay N. Cohn,Gilles R. Dagenais,Richard F. Davies,David E. Johnstone,C Fye,Sather,D Deykin,Gary S. Francis,Joseph Collins,William O. Williford,B N Singh +398 more
TL;DR: Digoxin did not reduce overall mortality, but it reduced the rate of hospitalization both overall and for worsening heart failure, which defines more precisely the role of digoxin in the management of chronic heart failure.
Journal ArticleDOI
Randomized, Placebo-Controlled Trial of Platelet Glycoprotein IIb/IIIa Blockade With Primary Angioplasty for Acute Myocardial Infarction
Sorin J. Brener,L. Barr,J. E. B. Burchenal,S. Katz,Barry S. George,A. A. Jones,E. D. Cohen,P. C. Gainey,H. J. White,H. B. Cheek,Jeffrey W. Moses,David J. Moliterno,Mark B. Effron,Eric J. Topol +13 more
TL;DR: Patients with acute MI of <12 hours’ duration were randomized to placebo or abciximab if they were deemed candidates for primary PTCA, and the primary efficacy end point was death, reinfarction, or any (urgent or elective) target vessel revascularization (TVR) at 6 months by intention-to-treat (ITT) analysis.
Journal ArticleDOI
Facilitated PCI in patients with ST-elevation myocardial infarction.
Stephen G. Ellis,Michal Tendera,Mark A. de Belder,Ad J. van Boven,Petr Widimsky,Luc Janssens,H. R. Andersen,Amadeo Betriu,Stefano Savonitto,Jerzy Adamus,Jan Z. Peruga,Maciej Kosmider,Olivier Katz,Thomas Neunteufl,Julia Jorgova,Maria Dorobantu,Liliana Grinfeld,Paul W. Armstrong,Bruce R. Brodie,Howard C. Herrmann,Gilles Montalescot,Franz-Josef Neumann,Mark B. Effron,Elliot S. Barnathan,Eric J. Topol +24 more
TL;DR: Neither facilitation of PCI with reteplase plus abcximab nor facilitation with abciximab alone significantly improved the clinical outcomes, as compared with ab ciximabs given at the time of PCI, in patients with ST-segment elevation myocardial infarction.
Journal ArticleDOI
Mechanisms of blood flow during cardiopulmonary resuscitation.
TL;DR: It appears that pressure generation and blood flow during CPR in the dog result from a generalized rise in intrathoracic pressure, not from direct cardiac compression, which can dramatically increase carotid blood flow During CPR.
Journal ArticleDOI
Emergency Administration of Abciximab for Treatment of Patients With Acute Ischemic Stroke: Results of an International Phase III Trial Abciximab in Emergency Treatment of Stroke Trial (AbESTT-II)
Harold P. Adams,Mark B. Effron,James C. Torner,Antoni Dávalos,Judith Frayne,Philip Teal,Jacques R. Leclerc,Barry Oemar,Lakshmi Padgett,Elliot S. Barnathan,Werner Hacke +10 more
TL;DR: This phase 3 trial did not demonstrate either safety or efficacy of intravenous administration of abciximab for the treatment of patients with acute ischemic stroke regardless of end point or population studied.