E
Edward B. Brown
Researcher at University of Rochester
Publications - 127
Citations - 11879
Edward B. Brown is an academic researcher from University of Rochester. The author has contributed to research in topics: Cancer & Breast cancer. The author has an hindex of 38, co-authored 121 publications receiving 10983 citations. Previous affiliations of Edward B. Brown include Manhattan College & Harvard University.
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Journal Article
The effect of digoxin on mortality and morbidity in patients with heart failure
Gilbert J. Perry,Edward B. Brown,R Thornton,T Shiva,J Hubbard,K R Reddy,J E Doherty,F P Cardello,A Fast,Martha J. Radford,J S Folger,G Bhaskar,R G Zoble,Sridharan,R R Loungani,Mihai Gheorghiade,A Hsieh,Carl L. Tommaso,M Mansuri,M A Guess,S Akhtar,Stefan Wagner,K Hagan,K M McIntyre,P Ruble,M Moten,A Riley,Gordon L. Pierpont,Anand,G Patel,B S Puram,BR Eladasari,J Karnegis,E Gillie,M H Crawford,W F Graettinger,A Shah,J Sacco,M A Chaudhry,D Dolen,N ElSherif,S BekheitSaad,E E Campos,J G Greene,Khanijo,U Kumar,G I Mallis,S Mookherjee,M DibnerDunlap,S C Gupta,K Danisa,U Thadani,A Tan,M Rajachar,M Amidi,M V OReilly,C A Hassapoyannes,M L Davies,V A Kumar,D Okerson,K B Ramanathan,B Putatunda,A Gollapudi,A Montero,Panchanan Mohanty,Charles Y. Lui,S Thagirisa,R W Lee,T R Glatter,K Bodine,D K Roberts,M Bertoglio,G W Dennish,R J Sarma,Gabriel Gregoratos,D C Rausch,W A Pitt,B M Kennelly,D Fahrenholtz,R Gordon,L Horwitz,R Rothbart,P Nutting,L Lutz,D L Copen,Andrew Rashkow,J Babb,L VanVoorhees,A Silverman,M E Stillabower,A B Miller,H T NguyenPho,R E Safford,S Fishman,J C Neiman,M Stein,JC Dominguez,G T Abernathy,P H Nair,L S Goodman,T H Cook,W Wickemeyer,D M Berkson,James Mathew,H G Richman,D L Lubell,R M Lang,E J Zajac,R Rosenstein,Marc A. Silver,J G Shanes,K J Kelly,M H Pequignot,Robert B. Campbell,P C Kirlin,D B Ziperman,D M Denny,L Gamble,Matthew C. Weiss,P K Kaimal,R W Dhurandhar,H Ventura,M L Godley,C Pu,E C Schick,D J Barbour,D Salmon,M Goldstein,Mark B. Effron,Jerome L. Fleg,K L Baughman,R Weiss,Keith M. Marzilli Ericson,W A Sturrock,J Heinsimer,G C Timmis,Sidney C. Smith,D D Shrestha,Wfc Duvernoy,J Hickner,B K Lewis,T K OBrien,S A Yarows,H J Willens,D J Mast,Thomas H. Johnson,RJ Rodeheffer,M Siefert,L Swenson,P Denes,R Gudapati,F R Charles,Michael W. Rich,Beckham,W P Hamilton,PB Abele,DM Harper,R L OKelly,A D Forker,F R Kahl,B W Garrou,TE Klang,K Popio,S Mohiuddin,E M Pollak,A Chiaramida,J J Gregory,L A Papa,J Abrams,S Ung,C K Jutila,R P Croke,S Chiaramida,R Lucariello,Da Rim,Mark Goldberger,R M Kohn,S Graham,Edward F. Philbin,K Sheesley,A Nafziger,G Macina,J T Hsueh,S Zoneraich,A Binder,C Weinstein,J Morrison,A Cameron,E J Vanderbush,J Brown,P N Pande,E Lader,R Kay,D Bloomfield,T Costantino,D E Heiselman,S Radwany,Smith,R E Hobbs,T D Fraker,T R Frerking,A C DeLeon,L G Christie,M Toren,J Grover,F D McBarron,D E Harris,R W McLean,L Morris,J Zatuchni,J P Boehmer,B S Clemson,H Lipshutz,R S Small,R Ufret,JE LugoRodriquez,A H Khan,M Yousefian,G C Friesinger,D Ely,JA Farmer,J B Young,R M Payne,R E Fowles,A B Lee,Y Shalev,AlBitar,G S Schroeder,L Radant,T L Hankey,S Rezkalla,D L Groden,K K Teo,DP Humen,D Wong,P V Greenwood,T Talibi,W Hui,WP Klinke,Mpj Senaratne,M Goeres,D F Hughes,Mar Sayeed,D L Roth,Belenkie,D E Manyari,K Borgersen,L Read,D Kinloch,R Reid,N C Barber,B A Horner,G Kenefick,R A Kuritzky,Imrie,K R Wagner,Simon W. Rabkin,H F Mizgala,L Tarry,A Dodek,J M Kornder,T Ashton,D M Barr,J Dufton,R Sweeny,A Morris,R Bessoudo,D Marr,Milton,B Thompson,Robinson,Bruce Sussex,M Tobin,D P McMahon,D Folkins,R Crowell,LD Lalonde,C Koilpillai,R J Hatheway,MG OReilly,T Machel,Hack,J W Stewart,Paul H. Tanser,B Sullivan,S Hagar,B Quinn,RA Davies,M G Baird,W L Williams,M Lemay,L Higginson,M Turek,R A Sochowski,A Weeks,M H Jacobs,R Baigrie,M A DeVilla,G Vertes,B Bozek,J E Goode,A J Ricci,J Swan,D A Fell,S N LevinoffRoth,Jmo Arnold,L Patrick,R F Southern,C Rinne,D Brisbin,J P DeYoung,T Baitz,S Vizel,J Minkowitz,P Letarte,Y K Chan,K K Kwok,S Nawaz,F Ganjavi,L Yao,J Misterski,D L Raco,A R Hess,G Kuruvilla,L Silverberg,D Borts,J C Fulop,M Weingert,R P Carter,B M Sahay,J E Hickey,G Lalonde,G Gosselin,Martial G. Bourassa,C Goulet,M Joyal,M Methe,G Honos,David Fitchett,A Serpa,F Sestier,G Roberge,Y Latour,C Rondeau,D Gossard,Jhf Lenis,R Brossoit,L Simard,F Delage,P. Auger,D Saulnier,P Talbot,J Beaudoin,J Campeau,G Pruneau,M Tamilia,G Boutros,B Comeau,R Starra,R StHilaire,J Veilleux,M Mercier,J F Poulin,K MacLellan,S Lepage,Jean L. Rouleau,N Bruinsma,C Levesque,R DeLarochelliere,M LeBlanc,S Kouz,G S Kiwan,M Laforest,J Brooks,G Bouchard,P B Gervais,James M. Brophy,J Gagnon,N Habib,A K Basu,A T Lutterodt,M Khouri,R Gorlin,Debra Egan,Rekha Garg,Salim Yusuf,T Montague,T W Smith,Jay N. Cohn,Gilles R. Dagenais,Richard F. Davies,David E. Johnstone,C Fye,Sather,D Deykin,Gary S. Francis,Joseph Collins,William O. Williford,B N Singh +398 more
TL;DR: Digoxin did not reduce overall mortality, but it reduced the rate of hospitalization both overall and for worsening heart failure, which defines more precisely the role of digoxin in the management of chronic heart failure.
Journal ArticleDOI
Mitochondrial membrane potential probes and the proton gradient: a practical usage guide.
TL;DR: This review will help illustrate both the strengths and potential pitfalls of common mitochondrial membrane potential dyes, and highlight best-usage approaches for their efficacious application in life sciences research.
Journal ArticleDOI
Lymphatic metastasis in the absence of functional intratumor lymphatics.
Timothy P. Padera,Ananth Kadambi,Emmanuelle di Tomaso,Carla Mouta Carreira,Edward B. Brown,Yves Boucher,Noah C. Choi,Douglas J. Mathisen,John C. Wain,Eugene J. Mark,Lance L. Munn,Rakesh K. Jain +11 more
TL;DR: Functional lymphatics associated with mouse tumors expressing normal or elevated levels of vascular endothelial growth factor–C (VEGF-C) are examined to suggest that the functional lymphatics in the tumor margin alone are sufficient for lymphatic metastasis and should be targeted therapeutically.
Journal ArticleDOI
Dynamic imaging of collagen and its modulation in tumors in vivo using second-harmonic generation.
Edward B. Brown,Trevor D. McKee,Emmanuelle diTomaso,Alain Pluen,Brian Seed,Yves Boucher,Rakesh K. Jain +6 more
TL;DR: It is shown that it is possible to optically image fibrillar collagen in tumors growing in mice using second-harmonic generation (SHG), which could offer basic scientists and clinicians an enhanced ability to estimate the relative penetrabilities of molecular therapeutics.
Journal ArticleDOI
Role of tumor-host interactions in interstitial diffusion of macromolecules: cranial vs. subcutaneous tumors.
Alain Pluen,Yves Boucher,Saroja Ramanujan,Trevor D. McKee,Takeshi Gohongi,Emmanuelle di Tomaso,Edward B. Brown,Yotaro Izumi,Robert B. Campbell,David A. Berk,Rakesh K. Jain +10 more
TL;DR: The results point to the necessity of developing site-specific drug carriers to improve the delivery of molecular medicine to solid tumors.