Mark D. Johnson

TL;DR: 11 different algorithms for analyzing array CGH data are compared, based on diverse techniques such as mixture models, Hidden Markov Models, maximum likelihood, regression, wavelets and genetic algorithms, to reveal general characteristics that are helpful to the biological investigator.

TL;DR: Despite a low-risk profile and few postoperative complications, patients in Africa were twice as likely to die after surgery when compared with the global average for postoperative deaths, and Initiatives to increase access to surgical treatments in Africa should be coupled with improved surveillance for deteriorating physiology in patients who develop postoperative complication.

TL;DR: Using an in vivo angiogenesis assay, the endothelial cell response to known angiogenic factors, basic fibroblast growth factor and adipocyte conditioned medium, was blocked by an inhibitor of matrix metalloproteinase activity, TIMP‐1.

TL;DR: The present studies demonstrate a general application of toxicogenomics that distinguishes two mechanistically unrelated classes of toxicants (cytotoxic anti-inflammatory drugs and DNA-damaging agents) based solely upon a cluster-type analysis of genes differentially induced or repressed in cultured cells during exposure to these compounds.

TL;DR: Dystrophin analysis is required for accurately distinguishing between Becker dystrophy and clinically similar autosomal recessive myopathies, and the correlation of both the biochemical and clinical data suggests that Duchenne/Becker Dystrophy can be divided into 4 clinically useful categories.