M
Mark Kuehnel
Researcher at Hannover Medical School
Publications - 38
Citations - 4420
Mark Kuehnel is an academic researcher from Hannover Medical School. The author has contributed to research in topics: Medicine & Biology. The author has an hindex of 7, co-authored 19 publications receiving 2671 citations. Previous affiliations of Mark Kuehnel include Hochschule Hannover & University of Mainz.
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Journal ArticleDOI
Pulmonary Vascular Endothelialitis, Thrombosis, and Angiogenesis in Covid-19.
Maximilian Ackermann,Stijn E. Verleden,Mark Kuehnel,Axel Haverich,Tobias Welte,Florian Laenger,Arno Vanstapel,Christopher Werlein,Helge Stark,Alexandar Tzankov,William W. Li,Vincent W. Li,Steven J. Mentzer,Danny Jonigk +13 more
TL;DR: In this small series, vascular angiogenesis distinguished the pulmonary pathobiology of Covid-19 from that of equally severe influenza virus infection.
Journal ArticleDOI
Morphomolecular motifs of pulmonary neoangiogenesis in interstitial lung diseases
Maximilian Ackermann,Maximilian Ackermann,Helge Stark,Lavinia Neubert,Stephanie Schubert,Paul Borchert,Friedemann Linz,Willi L. Wagner,W Stiller,Mark O. Wielpütz,Anne Hoefer,Axel Haverich,Steven J. Mentzer,Harshit R. Shah,Tobias Welte,Mark Kuehnel,Danny Jonigk +16 more
TL;DR: Three distinct manifestations of neoangiogenesis are identified as drivers of pulmonary remodelling in human ILDs, modulated by bone marrow-derived monocytes.
Journal ArticleDOI
Comparative analysis of morphological and molecular motifs in bronchiolitis obliterans and alveolar fibroelastosis after lung and stem cell transplantation
Danny Jonigk,Berenice Rath,Paul Borchert,Peter Braubach,Lavinia Maegel,Nicole Izykowski,Gregor Warnecke,Wiebke Sommer,Hans Kreipe,Robert Blach,Adrian Anklamm,Axel Haverich,Matthias Eder,Michael Stadler,Tobias Welte,Jens Gottlieb,Mark Kuehnel,Florian Laenger +17 more
TL;DR: An evolutionary model for the AFE pattern is described: a non‐specific fibrin‐rich reaction to injury pattern triggers a misguided resolution attempt and eventual progression towards manifest AFE.
Journal ArticleDOI
When tissue is the issue: a histological review of chronic lung allograft dysfunction
Stijn E. Verleden,Stijn E. Verleden,Jan H. von der Thüsen,Antoine Roux,Emily S Brouwers,Peter Braubach,Mark Kuehnel,Florian Laenger,Danny Jonigk +8 more
TL;DR: “Tissue remains the (main) issue,” as the authors are still limited in their knowledge about the actual triggers and specific mechanisms of all late forms of posttransplant graft failure, a shortcoming that needs to be addressed in order to further improve the outcome of lung transplant recipients.
Journal ArticleDOI
Airway remodelling in the transplanted lung.
TL;DR: The current state of the literature on chronic lung allograft dysfunction is reviewed and light is shed on classification systems, corresponding clinical and morphological changes, key cellular players and underlying molecular pathways, as well as on emerging diagnostic and therapeutic approaches.