M
Mark M. Kockx
Researcher at University of Antwerp
Publications - 159
Citations - 12365
Mark M. Kockx is an academic researcher from University of Antwerp. The author has contributed to research in topics: Apoptosis & Macrophage. The author has an hindex of 55, co-authored 153 publications receiving 11076 citations.
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Journal ArticleDOI
Autophagy in cardiovascular disease
TL;DR: Successful therapeutic approaches that regulate autophagy have been reported recently, suggesting that the autophagic machinery can be manipulated to treat heart failure or to prevent rupture of atherosclerotic plaques and sudden death.
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Platelet Phagocytosis and Processing of β-Amyloid Precursor Protein as a Mechanism of Macrophage Activation in Atherosclerosis
Guido R.Y. De Meyer,Dieter M. M. De Cleen,Susan Cooper,Michiel W.M. Knaapen,Dominique M. Jans,Wim Martinet,Arnold G. Herman,Hidde Bult,Mark M. Kockx +8 more
TL;DR: In vitro studies indicate that platelet phagocytosis leads to macrophage activation and suggest that Platelet-derived APP is proteolytically processed to A&bgr;, resulting in iNOS induction, a novel mechanism for macrophages activation in atherosclerosis.
Journal ArticleDOI
In Vivo Temperature Heterogeneity of Atherosclerotic Plaques Is Determined by Plaque Composition
TL;DR: In vivo temperature heterogeneity of rabbit atherosclerotic plaques is determined by plaque composition, and in vivo thermography may have important clinical implications in the assessment of plaque composition.
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In situ detection of starvation-induced autophagy.
TL;DR: The results suggest that LC3 immunostaining can be used as an alternative detection method for autophagy in situ, but only when this protein is overexpressed.
Journal ArticleDOI
Apoptosis in atherosclerosis: focus on oxidized lipids and inflammation.
Wim Martinet,Mark M. Kockx +1 more
TL;DR: Some of the most recent results concerning apoptosis in atherosclerosis are outlined with a special focus on oxidized lipids, inflammation and therapeutic regulation of the apoptotic cell death process.