M
Markus Glaß
Researcher at Martin Luther University of Halle-Wittenberg
Publications - 19
Citations - 910
Markus Glaß is an academic researcher from Martin Luther University of Halle-Wittenberg. The author has contributed to research in topics: microRNA & Gene expression. The author has an hindex of 9, co-authored 19 publications receiving 557 citations.
Papers
More filters
Journal ArticleDOI
IGF2BP1 promotes SRF-dependent transcription in cancer in a m6A- and miRNA-dependent manner
Simon Müller,Markus Glaß,Anurag Kumar Singh,Jacob Haase,Nadine Bley,Tommy Fuchs,Marcell Lederer,Andreas Dahl,Huilin Huang,Huilin Huang,Jianjun Chen,Jianjun Chen,Guido Posern,Stefan Hüttelmaier +13 more
TL;DR: Findings identify the SRF/IGF2BP1, miRNome- and m6A-dependent control of gene expression as a conserved oncogenic driver network in cancer.
Journal ArticleDOI
IGF2BP1 promotes cell migration by regulating MK5 and PTEN signaling
Nadine Stöhr,Marcel Köhn,Marcell Lederer,Markus Glaß,Claudia Reinke,Robert H. Singer,Stefan Hüttelmaier +6 more
TL;DR: This study reveals that IGF2BP1 promotes the velocity and directionality of tumor-derived cell migration by determining the cytoplasmic fate of two novel target mRNAs: MAPK4 and PTEN.
Journal ArticleDOI
Stress granules are dispensable for mRNA stabilization during cellular stress
Nadine Bley,Marcell Lederer,Birgit Pfalz,Claudia Reinke,Tommy Fuchs,Markus Glaß,Birgit Möller,Stefan Hüttelmaier +7 more
TL;DR: Findings indicate that the stabilization of mRNAs during cellular stress is facilitated by the formation of stable mRNPs, which are recruited to SGs by TIA proteins and/or G3BP1, which is dispensable for preventing mRNA degradation.
Journal ArticleDOI
IGF2BP1 enhances an aggressive tumor cell phenotype by impairing miRNA-directed downregulation of oncogenic factors.
Simon Müller,Nadine Bley,Markus Glaß,Bianca Busch,Vanessa Rousseau,Danny Misiak,Tommy Fuchs,Marcell Lederer,Stefan Hüttelmaier +8 more
TL;DR: Findings indicate that IGF2BP1 enhances an aggressive tumor cell phenotype by antagonizing miRNA-impaired gene expression.
Journal ArticleDOI
The oncogenic triangle of HMGA2, LIN28B and IGF2BP1 antagonizes tumor-suppressive actions of the let-7 family.
Bianca Busch,Nadine Bley,Simon Müller,Markus Glaß,Danny Misiak,Marcell Lederer,Martina Vetter,Hans-Georg Strauß,Christoph Thomssen,Stefan Hüttelmaier +9 more
TL;DR: The targeting of the HMGA2-LIN28B-IGF2BP1 triangle is suggested as a promising strategy in cancer treatment because the expression of the triangle factors is inversely correlated with let-7 levels and promoted by LIN28B impairingLet-7 biogenesis.