D
Danny Misiak
Researcher at Martin Luther University of Halle-Wittenberg
Publications - 28
Citations - 611
Danny Misiak is an academic researcher from Martin Luther University of Halle-Wittenberg. The author has contributed to research in topics: microRNA & Gene expression. The author has an hindex of 9, co-authored 26 publications receiving 373 citations.
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Journal ArticleDOI
AML1-ETO requires enhanced C/D box snoRNA/RNP formation to induce self-renewal and leukaemia
Fengbiao Zhou,Yi Liu,Yi Liu,Christian Rohde,Christian Rohde,Cornelius Pauli,Dennis Gerloff,Marcel Köhn,Danny Misiak,Nicole Bäumer,Chunhong Cui,Stefanie Göllner,Stefanie Göllner,Thomas Oellerich,Hubert Serve,Hubert Serve,Maria Paz Garcia-Cuellar,Robert K. Slany,Jaroslaw P. Maciejewski,Bartlomiej P Przychodzen,Barbara Seliger,Hans-Ulrich Klein,Hans-Ulrich Klein,Christoph Bartenhagen,Wolfgang E. Berdel,Martin Dugas,Makoto Mark Taketo,Daneyal Farouq,Schraga Schwartz,Aviv Regev,Aviv Regev,Aviv Regev,Josée Hébert,Guy Sauvageau,Caroline Pabst,Caroline Pabst,Stefan Hüttelmaier,Carsten Müller-Tidow,Carsten Müller-Tidow +38 more
TL;DR: Findings indicate that induction of C/D box snoRNA/RNP function constitutes an important pathway in leukaemogenesis, which is induced by oncogenes.
Journal ArticleDOI
IGF2BP1 enhances an aggressive tumor cell phenotype by impairing miRNA-directed downregulation of oncogenic factors.
Simon Müller,Nadine Bley,Markus Glaß,Bianca Busch,Vanessa Rousseau,Danny Misiak,Tommy Fuchs,Marcell Lederer,Stefan Hüttelmaier +8 more
TL;DR: Findings indicate that IGF2BP1 enhances an aggressive tumor cell phenotype by antagonizing miRNA-impaired gene expression.
Journal ArticleDOI
The oncogenic triangle of HMGA2, LIN28B and IGF2BP1 antagonizes tumor-suppressive actions of the let-7 family.
Bianca Busch,Nadine Bley,Simon Müller,Markus Glaß,Danny Misiak,Marcell Lederer,Martina Vetter,Hans-Georg Strauß,Christoph Thomssen,Stefan Hüttelmaier +9 more
TL;DR: The targeting of the HMGA2-LIN28B-IGF2BP1 triangle is suggested as a promising strategy in cancer treatment because the expression of the triangle factors is inversely correlated with let-7 levels and promoted by LIN28B impairingLet-7 biogenesis.
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Rapid identification of regulatory microRNAs by miTRAP (miRNA trapping by RNA in vitro affinity purification)
TL;DR: In this paper, the authors describe miTRAP (miRNA trapping by RNA in vitro affinity purification), an advanced protocol of previously reported MS2-tethering approaches that allows the rapid identification of miRNAs targeting an in vitro transcribed RNA in cell lysates.
Journal ArticleDOI
MiToBo - A Toolbox for Image Processing and Analysis
TL;DR: MiToBo is a toolbox and Java library for solving basic as well as advanced image processing and analysis tasks that builds upon and integrates into the widely-used image analysis software packages ImageJ and Fiji.