M
Markus Grompe
Researcher at Oregon Health & Science University
Publications - 323
Citations - 37404
Markus Grompe is an academic researcher from Oregon Health & Science University. The author has contributed to research in topics: Fanconi anemia & Stem cell. The author has an hindex of 88, co-authored 313 publications receiving 34220 citations. Previous affiliations of Markus Grompe include Northwestern University & University of North Carolina at Chapel Hill.
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Patent
Normalization of the enterohepatic circulation in animals with a chimeric humanized liver
TL;DR: In this article, a transgenic host animal, such as a mouse, that expresses human FGF19 that has normalized bile acid production when engrafted with human hepatocytes was described.
Patent
Monoclonal antibodies specific for pancreatic endocrine, exocrine or ductal cell
Markus Grompe,Philip R. Streeter,Craig Dorrell,Stephanie L. Abraham,Kelsea M. Lanxon-Cookson +4 more
TL;DR: Isolated monoclonal antibodies can be conjugated to an effector molecule, such as a detectable marker, a therapeutic agent, or a toxin this article, which can be used to detect and isolate pancreatic cells or a subset thereof.
Journal ArticleDOI
Embryonic stem cells can be used to construct hybrid cell lines containing a single, selectable murine chromosome.
TL;DR: To produce mouse monochromosomal donor hybrids, embryonic stem cells with targeted gene disruptions of known chromosomal location as starting material were utilized and can be used to generate a complete panel of marked mouse chromosomes for somatic cell genetic experimentaion.
Journal Article
Rapid assessment of fanconi pathway function: A new diagnostic approach to fanconi anemia
W. Nicholas Haining,Lisa A. Moreau,Toshiyasu Taniguchi,Rocío Montes de Oca,Irene García-Higuera,Eva C. Guinan,Markus Grompe,Alan D. D'Andrea +7 more
Journal ArticleDOI
Alternative energy for embryonic stem cell research
TL;DR: The ethical concerns regarding the destruction of human life outweigh the potential benefits of producing new embryo-derived cell lines, so research into these lines is discouraged.