E
Ernesto De Menis
Researcher at University of Helsinki
Publications - 33
Citations - 2759
Ernesto De Menis is an academic researcher from University of Helsinki. The author has contributed to research in topics: Acromegaly & Pituitary adenoma. The author has an hindex of 19, co-authored 31 publications receiving 2530 citations.
Papers
More filters
Journal ArticleDOI
Pituitary Adenoma Predisposition Caused by Germline Mutations in the AIP Gene
Outi Vierimaa,Marianthi Georgitsi,Rainer Lehtonen,Pia Vahteristo,Antti Kokko,Anniina Raitila,Karoliina Tuppurainen,Tapani Ebeling,Pasi I. Salmela,Ralf Paschke,Sadi Gundogdu,Ernesto De Menis,Markus J. Mäkinen,Virpi Launonen,Auli Karhu,Lauri A. Aaltonen +15 more
TL;DR: Combining chip-based technologies with genealogy data, germline mutations in the aryl hydrocarbon receptor interacting protein (AIP) gene in individuals with pituitary adenoma predisposition (PAP) are identified.
Journal ArticleDOI
Residual pituitary function after brain injury-induced hypopituitarism: A prospective 12-month study
Gianluca Aimaretti,Maria Rosaria Ambrosio,Carolina Di Somma,Maurizio Gasperi,Salvatore Cannavò,Carla Scaroni,Alessandra Fusco,Patrizia Del Monte,Ernesto De Menis,Marco Faustini-Fustini,Franco Grimaldi,Francesco Logoluso,P. Razzore,S. Rovere,Salvatore Benvenga,Ettore C. degli Uberti,Laura De Marinis,Gaetano Lombardi,Franco Mantero,Enio Martino,Giulio Giordano,Ezio Ghigo +21 more
TL;DR: There is high risk for H in TBI and SAH patients and early diagnosis of PH is always confirmed in the long term, whereas MH and IH were confirmed in 25% only.
Journal ArticleDOI
Clinical Characteristics and Therapeutic Responses in Patients with Germ-Line AIP Mutations and Pituitary Adenomas: An International Collaborative Study
Adrian Daly,Maria A. Tichomirowa,Patrick Petrossians,Elina Heliövaara,Marie Lise Jaffrain-Rea,Anne Barlier,Luciana Ansaneli Naves,Tapani Ebeling,Auli Karhu,Antti Raappana,Laure Cazabat,Ernesto De Menis,Carmen Fajardo Montañana,Gérald Raverot,Robert J. Weil,Timo Sane,Dominique Maiter,Sebastian J C M M Neggers,Maria Yaneva,AntoineAntoine Tabarin,Elisa Verrua,Eija Eloranta,Arnaud Murat,Outi Vierimaa,Pasi I. Salmela,Philippe Emy,Rodrigo A. Toledo,Maria Isabel Sabaté,Chiara Villa,Chiara Villa,Marc Popelier,Roberto Salvatori,Juliet Jennings,Ángel Ferrández Longás,José Ignacio Labarta Aizpún,Marianthi Georgitsi,Ralf Paschke,Cristina L. Ronchi,Matti Välimäki,Carola Saloranta,Wouter W. de Herder,Renato Cozzi,Mirtha Guitelman,Flavia Magri,Maria Stefania Lagonigro,Georges Halaby,Vinciane Corman,Marie-Thérèse Hagelstein,Jean-Francis Vanbellinghen,Gustavo Barcelos Barra,Anne-Paule Gimenez-Roqueplo,Fergus J. Cameron,Françoise Borson-Chazot,Ian M. Holdaway,Sergio P. A. Toledo,Günter K. Stalla,Anna Spada,Sabina Zacharieva,Jérôme Bertherat,Thierry Brue,Vincent Bours,Philippe Chanson,Lauri A. Aaltonen,Albert Beckers +63 more
TL;DR: Prisposition for aggressive disease in young patients, often in a familial setting, suggests that earlier diagnosis of AIPmut pituitary adenomas may have clinical utility.
Journal ArticleDOI
Germline CDKN1B/p27Kip1 mutation in multiple endocrine neoplasia.
Marianthi Georgitsi,Anniina Raitila,Auli Karhu,Rob B. van der Luijt,Cora M. Aalfs,Timo Sane,Outi Vierimaa,Markus J. Mäkinen,Karoliina Tuppurainen,Ralph Paschke,Oliver Gimm,Christian A. Koch,Sadi Gundogdu,Anneke Lucassen,Marc Tischkowitz,Louise Izatt,Simon Aylwin,Gul Bano,Shirley Hodgson,Ernesto De Menis,Virpi Launonen,Pia Vahteristo,Lauri A. Aaltonen +22 more
TL;DR: The results support the previous finding that germline CDKN1B/p27(Kip1) mutations predispose to a human MEN1-like condition.
Journal ArticleDOI
Molecular diagnosis of pituitary adenoma predisposition caused by aryl hydrocarbon receptor-interacting protein gene mutations.
Marianthi Georgitsi,Anniina Raitila,Auli Karhu,Karoliina Tuppurainen,Markus J. Mäkinen,Outi Vierimaa,Ralf Paschke,Wolfgang Saeger,Rob B. van der Luijt,Timo Sane,Mercedes Robledo,Ernesto De Menis,Robert J. Weil,A. Wasik,Grzegorz Zieliński,Olga Lucewicz,Jan Lubinski,Virpi Launonen,Pia Vahteristo,Lauri A. Aaltonen +19 more
TL;DR: AIP IHC, followed by genetic counseling and possible AIP mutation analysis in IHC-negative cases, appears feasible in identification of PAP, a procedure similar to the diagnostics of the Lynch syndrome.