S
Saila Kauppila
Researcher at Oulu University Hospital
Publications - 64
Citations - 4068
Saila Kauppila is an academic researcher from Oulu University Hospital. The author has contributed to research in topics: Breast cancer & Cancer. The author has an hindex of 30, co-authored 59 publications receiving 3699 citations. Previous affiliations of Saila Kauppila include Netherlands Cancer Institute & University of Oulu.
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Journal ArticleDOI
Multiple independent variants at the TERT locus are associated with telomere length and risks of breast and ovarian cancer
Stig E. Bojesen,Stig E. Bojesen,Karen A. Pooley,Sharon E. Johnatty,Jonathan Beesley,Kyriaki Michailidou,Jonathan Tyrer,Stacey L. Edwards,Hilda A. Pickett,Hilda A. Pickett,Howard C. Shen,Chanel E. Smart,Kristine M. Hillman,Phuong L. Mai,Kate Lawrenson,Michael D. Stutz,Michael D. Stutz,Yi Lu,Rod Karevan,Nicholas T. Woods,Rebecca L. Johnston,Juliet D. French,Xiaoqing Chen,Maren Weischer,Sune F. Nielsen,Melanie Maranian,Maya Ghoussaini,Shahana Ahmed,Caroline Baynes,Manjeet K. Bolla,Qin Wang,Joe Dennis,Lesley McGuffog,Daniel Barrowdale,Andrew Lee,Sue Healey,Michael Lush,Daniel C. Tessier,Daniel Vincent,Françis Bacot,Ignace Vergote,Sandrina Lambrechts,Evelyn Despierre,Harvey A. Risch,Anna González-Neira,Mary Anne Rossing,Mary Anne Rossing,Guillermo Pita,Jennifer A. Doherty,Nuria Álvarez,Melissa C. Larson,Brooke L. Fridley,Nils Schoof,Jenny Chang-Claude,Mine S. Cicek,Julian Peto,Kimberly R. Kalli,Annegien Broeks,Sebastian M. Armasu,Marjanka K. Schmidt,Linde M. Braaf,Boris Winterhoff,Heli Nevanlinna,Gottfried E. Konecny,Diether Lambrechts,L. Rogmann,Pascal Guénel,Attila Teoman,Roger L. Milne,Joaquin J. Garcia,Angela Cox,Vijayalakshmi Shridhar,Barbara Burwinkel,Frederik Marmé,Rebecca Hein,Rebecca Hein,Elinor J. Sawyer,Christopher A. Haiman,Shan Wang-Gohrke,Irene L. Andrulis,Kirsten B. Moysich,John L. Hopper,Kunle Odunsi,Annika Lindblom,Graham G. Giles,Graham G. Giles,Graham G. Giles,Hermann Brenner,Jacques Simard,Galina Lurie,Peter A. Fasching,Peter A. Fasching,Michael E. Carney,Paolo Radice,Lynne R. Wilkens,Anthony J. Swerdlow,Marc T. Goodman,Hiltrud Brauch,Hiltrud Brauch,Montserrat Garcia-Closas,Peter Hillemanns,Robert Winqvist,Matthias Dürst,Peter Devilee,Ingo B. Runnebaum,Anna Jakubowska,Jan Lubinski,Arto Mannermaa,Ralf Bützow,Natalia Bogdanova,Thilo Dörk,Liisa M. Pelttari,Wei Zheng,Arto Leminen,Hoda Anton-Culver,Clareann H. Bunker,Vessela N. Kristensen,Roberta B. Ness,Kenneth Muir,Kenneth Muir,Robert Edwards,Alfons Meindl,Florian Heitz,Keitaro Matsuo,Andreas du Bois,Anna H. Wu,Philipp Harter,Soo Hwang Teo,Ira Schwaab,Xiao-Ou Shu,William Blot,Satoyo Hosono,Daehee Kang,Toru Nakanishi,Mikael Hartman,Mikael Hartman,Yasushi Yatabe,Ute Hamann,Beth Y. Karlan,Suleeporn Sangrajrang,Susanne K. Kjaer,Valerie Gaborieau,Allan Jensen,Diana Eccles,Estrid Høgdall,Chen-Yang Shen,Chen-Yang Shen,Judith E. Brown,Yin Ling Woo,Mitul Shah,Mat Adenan Noor Azmi,Robert Luben,Siti Zawiah Omar,Kamila Czene,Robert A. Vierkant,Børge G. Nordestgaard,Henrik Flyger,Celine M. Vachon,Janet E. Olson,Xianshu Wang,Douglas A. Levine,Anja Rudolph,Rachel Palmieri Weber,Dieter Flesch-Janys,Edwin S. Iversen,Stefan Nickels,Joellen M. Schildkraut,Isabel dos Santos Silva,Daniel W. Cramer,Lorna Gibson,Kathryn L. Terry,Olivia Fletcher,Allison F. Vitonis,C. Ellen van der Schoot,Elizabeth M. Poole,Frans B. L. Hogervorst,Shelley S. Tworoger,Jianjun Liu,Elisa V. Bandera,Jingmei Li,Sara H. Olson,Keith Humphreys,Irene Orlow,Carl Blomqvist,Lorna Rodriguez-Rodriguez,Kristiina Aittomäki,Helga B. Salvesen,Taru A. Muranen,Elisabeth Wik,Barbara Brouwers,Camilla Krakstad,Els Wauters,Mari K. Halle,Hans Wildiers,Lambertus A. Kiemeney,Claire Mulot,Katja K.H. Aben,Pierre Laurent-Puig,Anne M. van Altena,Thérèse Truong,Leon F.A.G. Massuger,Javier Benitez,Tanja Pejovic,Jose Ignacio Arias Perez,Maureen E. Hoatlin,M. Pilar Zamora,Linda S. Cook,Sabapathy P. Balasubramanian,Linda E. Kelemen,Andreas Schneeweiss,Nhu D. Le,Christof Sohn,Angela Brooks-Wilson,Angela Brooks-Wilson,Ian Tomlinson,Michael J. Kerin,Nicola Miller,Cezary Cybulski,Brian E. Henderson,Janusz Menkiszak,Fredrick R. Schumacher,Nicolas Wentzensen,Loic Le Marchand,Hannah P. Yang,Anna Marie Mulligan,Gord Glendon,Svend Aage Engelholm,Julia A. Knight,Claus Høgdall,Carmel Apicella,Martin Gore,Helen Tsimiklis,Honglin Song,Melissa C. Southey,Agnes Jager,Ans M Wvan Den Ouweland,Robert S. Brown,John W.M. Martens,James M. Flanagan,Mieke Kriege,James Paul,Sara Margolin,Nadeem Siddiqui,Gianluca Severi,Gianluca Severi,Alice S. Whittemore,Laura Baglietto,Laura Baglietto,Valerie McGuire,Christa Stegmaier,Weiva Sieh,Heiko Müller,Volker Arndt,Yu Tang Gao,Mark S. Goldberg,Gong Yang,Martine Dumont,John R. McLaughlin,Arndt Hartmann,Arif B. Ekici,Matthias W. Beckmann,Catherine M. Phelan,Michael P. Lux,Jenny Permuth-Wey,Bernard Peissel,Thomas A. Sellers,Filomena Ficarazzi,Monica Barile,Argyrios Ziogas,Alan Ashworth,Aleksandra Gentry-Maharaj,Michael Jones,Susan J. Ramus,Nick Orr,Usha Menon,Celeste Leigh Pearce,Thomas Brüning,Malcolm C. Pike,Malcolm C. Pike,Yon Ko,Jolanta Lissowska,Jonine D. Figueroa,Jolanta Kupryjanczyk,Stephen J. Chanock,Agnieszka Dansonka-Mieszkowska,Arja Jukkola-Vuorinen,Iwona K. Rzepecka,Katri Pylkäs,Mariusz Bidziński,Saila Kauppila,Antoinette Hollestelle,Caroline Seynaeve,Rob A. E. M. Tollenaar,Katarzyna Durda,Katarzyna Jaworska,Katarzyna Jaworska,Jaana M. Hartikainen,Veli-Matti Kosma,Vesa Kataja,Natalia Antonenkova,Jirong Long,Martha J. Shrubsole,Sandra Deming-Halverson,Artitaya Lophatananon,Artitaya Lophatananon,Pornthep Siriwanarangsan,Sarah Stewart-Brown,Nina Ditsch,Peter Lichtner,Rita K. Schmutzler,Hidemi Ito,Hiroji Iwata,Kazuo Tajima,Chiu-Chen Tseng,Daniel O. Stram,David Van Den Berg,Cheng Har Yip,M. Kamran Ikram,Yew Ching Teh,Hui Cai,Wei Lu,Lisa B. Signorello,Qiuyin Cai,Dong Young Noh,Keun-Young Yoo,Hui Miao,Philip Iau,Yik Ying Teo,James McKay,Charles L. Shapiro,Foluso O. Ademuyiwa,George Fountzilas,Chia-Ni Hsiung,Jyh Cherng Yu,Ming-Feng Hou,Catherine S. Healey,Craig Luccarini,Susan Peock,Dominique Stoppa-Lyonnet,Paolo Peterlongo,Timothy R. Rebbeck,Marion Piedmonte,Christian F. Singer,Eitan Friedman,Mads Thomassen,Kenneth Offit,Thomas Hansen,Susan L. Neuhausen,Csilla Szabo,Ignacio Blanco,Judy Garber,Steven A. Narod,Jeffrey N. Weitzel,Marco Montagna,Edith Olah,Andrew K. Godwin,Drakoulis Yannoukakos,David E. Goldgar,Trinidad Caldés,Evgeny N. Imyanitov,Laima Tihomirova,Banu Arun,Ian G. Campbell,Arjen R. Mensenkamp,Christi J. van Asperen,Kees E. P. van Roozendaal,Hanne Meijers-Heijboer,J. Margriet Collée,Jan C. Oosterwijk,Maartje J. Hooning,Matti A. Rookus,Rob B. van der Luijt,Theo A. Mvan Os,D. Gareth Evans,Debra Frost,Elena Fineberg,Julian Barwell,Lisa Walker,M. John Kennedy,Radka Platte,Rosemarie Davidson,Steve Ellis,Trevor Cole,Brigitte Bressac-de Paillerets,Bruno Buecher,Francesca Damiola,Laurence Faivre,Marc Frenay,Olga M. Sinilnikova,Olivier Caron,Sophie Giraud,Sylvie Mazoyer,Valérie Bonadona,Virginie Caux-Moncoutier,Aleksandra Tołoczko-Grabarek,Jacek Gronwald,Tomasz Byrski,Amanda B. Spurdle,Bernardo Bonanni,Daniela Zaffaroni,Giuseppe Giannini,Loris Bernard,Riccardo Dolcetti,Siranoush Manoukian,Norbert Arnold,Christoph Engel,Helmut Deissler,Kerstin Rhiem,Dieter Niederacher,Hansjoerg Plendl,Christian Sutter,Barbara Wappenschmidt,Åke Borg,Beatrice Melin,Johanna Rantala,Maria Soller,Katherine L. Nathanson,Susan M. Domchek,Gustavo C. Rodriguez,Ritu Salani,Daphne Gschwantler Kaulich,Muy Kheng Tea,Shani Shimon Paluch,Yael Laitman,Anne-Bine Skytte,Torben A Kruse,Uffe Birk Jensen,Mark E. Robson,Anne-Marie Gerdes,Bent Ejlertsen,Lenka Foretova,Sharon A. Savage,Jenny Lester,Penny Soucy,Karoline Kuchenbaecker,Curtis Olswold,Julie M. Cunningham,Susan L. Slager,Vernon S. Pankratz,Ed Dicks,Sunil R. Lakhani,Sunil R. Lakhani,Fergus J. Couch,Per Hall,Alvaro N.A. Monteiro,Simon A. Gayther,Paul D.P. Pharoah,Roger R. Reddel,Roger R. Reddel,Ellen L. Goode,Mark H. Greene,Douglas F. Easton,Andrew Berchuck,Antonis C. Antoniou,Georgia Chenevix-Trench,Alison M. Dunning +455 more
TL;DR: Using the Illumina custom genotyping array iCOGs, SNPs at the TERT locus in breast, ovarian and BRCA1 mutation carrier cancer cases and controls and leukocyte telomere measurements are analyzed to find associations cluster into three independent peaks.
Journal ArticleDOI
Genome-wide association studies identify four ER negative-specific breast cancer risk loci
Montserrat Garcia-Closas,Fergus J. Couch,Sara Lindström,Kyriaki Michailidou,Marjanka K. Schmidt,Mark N. Brook,Nick Orr,Suhn K. Rhie,Elio Riboli,Heather Spencer Feigelson,Loic Le Marchand,Julie E. Buring,Diana Eccles,Penelope Miron,Peter A. Fasching,Peter A. Fasching,Hiltrud Brauch,Hiltrud Brauch,Jenny Chang-Claude,Jane Carpenter,Andrew K. Godwin,Heli Nevanlinna,Graham G. Giles,Graham G. Giles,Angela Cox,John L. Hopper,Manjeet K. Bolla,Qin Wang,Joe Dennis,Ed Dicks,William J. Howat,Nils Schoof,Stig E. Bojesen,Stig E. Bojesen,Diether Lambrechts,Diether Lambrechts,Annegien Broeks,Irene L. Andrulis,Pascal Guénel,Pascal Guénel,Barbara Burwinkel,Barbara Burwinkel,Elinor J. Sawyer,Antoinette Hollestelle,Olivia Fletcher,Robert Winqvist,Hermann Brenner,Arto Mannermaa,Ute Hamann,Alfons Meindl,Annika Lindblom,Wei Zheng,Peter Devillee,Peter Devillee,Mark S. Goldberg,Jan Lubinski,Vessela N. Kristensen,Anthony J. Swerdlow,Hoda Anton-Culver,Thilo Dörk,Kenneth Muir,Kenneth Muir,Keitaro Matsuo,Anna H. Wu,Paolo Radice,Soo Hwang Teo,Xiao-Ou Shu,William Blot,Daehee Kang,Mikael Hartman,Suleeporn Sangrajrang,Chen-Yang Shen,Chen-Yang Shen,Melissa C. Southey,Daniel J. Park,Fleur Hammet,Jennifer Stone,Laura J. van't Veer,Emiel J. Th. Rutgers,Artitaya Lophatananon,Sarah Stewart-Brown,Pornthep Siriwanarangsan,Julian Peto,Michael G. Schrauder,Arif B. Ekici,Matthias W. Beckmann,Isabel dos Santos Silva,Nichola Johnson,Helen R. Warren,Ian Tomlinson,Michael J. Kerin,Nicola Miller,Federick Marme,Andreas Schneeweiss,Christof Sohn,Thérèse Truong,Thérèse Truong,Pierre Laurent-Puig,Pierre Kerbrat,Børge G. Nordestgaard,Sune F. Nielsen,Henrik Flyger,Roger L. Milne,Jose Ignacio Arias Perez,Primitiva Menéndez,Heiko Müller,Volker Arndt,Christa Stegmaier,Peter Lichtner,Magdalena Lochmann,Christina Justenhoven,Christina Justenhoven,Yon Ko,Taru A. Muranen,Kristiina Aittomäki,Carl Blomqvist,Dario Greco,Tuomas Heikkinen,Hidemi Ito,Hiroji Iwata,Yasushi Yatabe,Natalia Antonenkova,Sara Margolin,Vesa Kataja,Veli-Matti Kosma,Jaana M. Hartikainen,Rosemary L. Balleine,Chiu-Chen Tseng,David Van Den Berg,Daniel O. Stram,Patrick Neven,Anne Sophie Dieudonne,Karin Leunen,Anja Rudolph,Stefan Nickels,Dieter Flesch-Janys,Paolo Peterlongo,Bernard Peissel,Loris Bernard,Janet E. Olson,Xianshu Wang,Kristen N. Stevens,Gianluca Severi,Gianluca Severi,Laura Baglietto,Laura Baglietto,Catriona McLean,Gerhard A. Coetzee,Ye Feng,Brian E. Henderson,Fredrick R. Schumacher,Natalia Bogdanova,Martine Dumont,Cheng Har Yip,Nur Aishah Taib,Ching-Yu Cheng,Martha J. Shrubsole,Jirong Long,Katri Pylkäs,Arja Jukkola-Vuorinen,Saila Kauppila,Julia A. Knight,Gord Glendon,Anna Marie Mulligan,R.A.E.M. Tollenaar,Caroline M. Seynaeve,Mieke Kriege,Maartje J. Hooning,Ans M.W. van den Ouweland,Carolien H.M. van Deurzen,Wei Lu,Yu Tang Gao,Hui Cai,Sabapathy P. Balasubramanian,Simon S. Cross,Malcolm W.R. Reed,Lisa B. Signorello,Qiuyin Cai,Mitul Shah,Hui Miao,Ching Wan Chan,Kee Seng Chia,Anna Jakubowska,Katarzyna Jaworska,Katarzyna Durda,Chia-Ni Hsiung,Pei Ei Wu,Jyh Cherng Yu,Alan Ashworth,Michael Jones,Daniel C. Tessier,Anna González-Neira,Guillermo Pita,M. Rosario Alonso,Daniel Vincent,Francois Bacot,Christine B. Ambrosone,Elisa V. Bandera,Esther M. John,Esther M. John,Gary K. Chen,Jennifer J. Hu,Jorge L. Rodriguez-Gil,Leslie Bernstein,Michael F. Press,Regina G. Ziegler,Robert M. Millikan,Sandra Deming-Halverson,Sarah J. Nyante,Sue A. Ingles,Quinten Waisfisz,Helen Tsimiklis,Enes Makalic,Daniel F. Schmidt,Minh Bui,Lorna Gibson,Bertram Müller-Myhsok,Rita K. Schmutzler,Rebecca Hein,Rebecca Hein,Norbert Dahmen,Lars Beckmann,Kirsimari Aaltonen,Kamila Czene,Astrid Irwanto,Jianjun Liu,Clare Turnbull,Nazneen Rahman,Hanne Meijers-Heijboer,André G. Uitterlinden,Fernando Rivadeneira,Curtis Olswold,Susan L. Slager,Robert Pilarski,Foluso O. Ademuyiwa,Irene Konstantopoulou,Nicholas G. Martin,Grant W. Montgomery,Dennis J. Slamon,Claudia Rauh,Michael P. Lux,Sebastian M. Jud,Thomas Brüning,JoEllen Weaver,Priyanka Sharma,Harsh B. Pathak,William J. Tapper,Sue Gerty,Lorraine Durcan,Dimitrios Trichopoulos,Dimitrios Trichopoulos,Rosario Tumino,Petra H.M. Peeters,Rudolf Kaaks,Daniele Campa,Federico Canzian,Elisabete Weiderpass,Mattias Johansson,Kay-Tee Khaw,Ruth C. Travis,Françoise Clavel-Chapelon,Françoise Clavel-Chapelon,Laurence N. Kolonel,Constance Chen,Andrew H. Beck,Susan E. Hankinson,Susan E. Hankinson,Christine D. Berg,Robert N. Hoover,Jolanta Lissowska,Jonine D. Figueroa,Daniel I. Chasman,Mia M. Gaudet,W. Ryan Diver,Walter C. Willett,David J. Hunter,Jacques Simard,Javier Benitez,Alison M. Dunning,Mark E. Sherman,Georgia Chenevix-Trench,Stephen J. Chanock,Per Hall,Paul D.P. Pharoah,Celine M. Vachon,Douglas F. Easton,Christopher A. Haiman,Peter Kraft +287 more
TL;DR: SNPs at four loci were associated with ER-negative but not ER-positive breast cancer (P > 0.05), providing further evidence for distinct etiological pathways associated with invasive ER- positive and ER- negative breast cancers.
Journal ArticleDOI
Inflammation and prognosis in colorectal cancer.
Kai Klintrup,Johanna M. Mäkinen,Saila Kauppila,Päivi Väre,Jukka Melkko,Hannu Tuominen,Karoliina Tuppurainen,Jyrki Mäkelä,Tuomo J. Karttunen,Markus J. Mäkinen +9 more
TL;DR: Inflammatory cell response at the invasive border is a relevant prognostic indicator and could be easily incorporated into the routine evaluation of histopathological specimens.
Journal ArticleDOI
Genome-wide association analysis identifies three new breast cancer susceptibility loci
Maya Ghoussaini,Olivia Fletcher,Kyriaki Michailidou,Clare Turnbull,Marjanka K. Schmidt,Ed Dicks,Joe Dennis,Qin Wang,Manjeet K. Humphreys,Craig Luccarini,Caroline Baynes,Don M. Conroy,Melanie Maranian,Shahana Ahmed,Kristy Driver,Nichola Johnson,Nick Orr,Isabel dos Santos Silva,Quinten Waisfisz,Hanne Meijers-Heijboer,André G. Uitterlinden,Fernando Rivadeneira,Per Hall,Kamila Czene,Astrid K. Irwanto,Jianjun Liu,Heli Nevanlinna,Kristiina Aittomäki,Carl Blomqvist,Alfons Meindl,Rita K. Schmutzler,Bertram Müller-Myhsok,Peter Lichtner,Jenny Chang-Claude,Rebecca Hein,Stefan Nickels,Dieter Flesch-Janys,Helen Tsimiklis,Enes Makalic,Daniel F. Schmidt,Minh Bui,John L. Hopper,Carmel Apicella,Daniel J. Park,Melissa C. Southey,David J. Hunter,Stephen J. Chanock,Annegien Broeks,Senno Verhoef,Frans B. L. Hogervorst,Peter A. Fasching,Michael P. Lux,Matthias W. Beckmann,Arif B. Ekici,Elinor J. Sawyer,Elinor J. Sawyer,Ian Tomlinson,Michael J. Kerin,Frederik Marmé,Andreas Schneeweiss,Christof Sohn,Barbara Burwinkel,Barbara Burwinkel,Pascal Guénel,Pascal Guénel,Thérèse Truong,Thérèse Truong,Emilie Cordina-Duverger,Emilie Cordina-Duverger,Florence Menegaux,Florence Menegaux,Stig E. Bojesen,Børge G. Nordestgaard,Sune F. Nielsen,Henrik Flyger,Roger L. Milne,M. Rosario Alonso,Anna González-Neira,Javier Benitez,Hoda Anton-Culver,Argyrios Ziogas,Leslie Bernstein,Christina Clarke Dur,Hermann Brenner,Heiko Müller,Volker Arndt,Christa Stegmaier,Christina Justenhoven,Christina Justenhoven,Hiltrud Brauch,Hiltrud Brauch,Thomas Brüning,Shan Wang-Gohrke,Ursula Eilber,Thilo Dörk,Peter Schürmann,Michael Bremer,Peter Hillemanns,Natalia Bogdanova,Natalia Antonenkova,Yuri I. Rogov,Johann H. Karstens,Marina Bermisheva,Darya Prokofieva,Elza Khusnutdinova,Annika Lindblom,Sara Margolin,Arto Mannermaa,Vesa Kataja,Veli-Matti Kosma,Jaana M. Hartikainen,Diether Lambrechts,Betül T. Yesilyurt,Giuseppe Floris,Karin Leunen,Siranoush Manoukian,Bernardo Bonanni,Stefano Fortuzzi,Paolo Peterlongo,Fergus J. Couch,Xianshu Wang,Kristen N. Stevens,Adam M. Lee,Graham G. Giles,Graham G. Giles,Laura Baglietto,Laura Baglietto,Gianluca Severi,Gianluca Severi,Catriona McLean,Grethe I. Grenaker Alnæs,Vessela N. Kristensen,Vessela N. Kristensen,Anne-Lise Børrensen-Dale,Anne-Lise Børrensen-Dale,Esther M. John,Esther M. John,Alexander Miron,Robert Winqvist,Katri Pylkäs,Arja Jukkola-Vuorinen,Saila Kauppila,Irene L. Andrulis,Irene L. Andrulis,Gord Glendon,Anna Marie Mulligan,Anna Marie Mulligan,Peter Devilee,Christie J. van Asperen,Rob A. E. M. Tollenaar,Caroline Seynaeve,Jonine D. Figueroa,Montserrat Garcia-Closas,Louise A. Brinton,Jolanta Lissowska,Maartje J. Hooning,Antoinette Hollestelle,Rogier A. Oldenburg,Ans M.W. van den Ouweland,Angela Cox,Malcolm W.R. Reed,Mitul Shah,A Jakubowska,Jan Lubinski,Katarzyna Jaworska,Katarzyna Durda,Michael Jones,Minouk J. Schoemaker,Alan Ashworth,Anthony J. Swerdlow,Jonathan Beesley,Xiaoqing Chen,Kenneth Muir,Artitaya Lophatananon,Suthee Rattanamongkongul,Arkom Chaiwerawattana,Daehee Kang,Keun-Young Yoo,Dong-Young Noh,Chen-Yang Shen,Jyh-Cherng Yu,Pei-Ei Wu,Chia-Ni Hsiung,Annie Perkins,Ruth Swann,Louiza S. Velentzis,Diana Eccles,William J. Tapper,S Gerty,Nikki Graham,Bruce A.J. Ponder,Georgia Chenevix-Trench,Paul D.P. Pharoah,Mark Lathrop,Alison M. Dunning,Nazneen Rahman,Julian Peto,Douglas F. Easton +197 more
TL;DR: Three new breast cancer risk loci are identified at 12p11, 12q24 and 21q21, which lie in regions that contain strong plausible candidate genes: PTHLH has a crucial role in mammary gland development and the establishment of bone metastasis in breast cancer, and NRIP1 encodes an ER cofactor and has a role in the regulation of breast cancer cell growth.
Journal ArticleDOI
Immunoassay for intact amino-terminal propeptide of human type I procollagen.
TL;DR: In this paper, the intact, trimeric amino-terminal propeptide of human type I procollagen (PINP) and its Col1 domain was isolated from the pleural fluids of cancer patients by a combination of ion-exchange, gel-filtration, and reversed-phase chromatographies.