M
Marlene Kolitzus
Researcher at University Hospital Regensburg
Publications - 1
Citations - 948
Marlene Kolitzus is an academic researcher from University Hospital Regensburg. The author has contributed to research in topics: Interleukin 21 & Interleukin 12. The author has an hindex of 1, co-authored 1 publications receiving 591 citations.
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LDHA-Associated Lactic Acid Production Blunts Tumor Immunosurveillance by T and NK Cells.
Almut Brand,Katrin Singer,Gudrun E. Koehl,Marlene Kolitzus,Gabriele Schoenhammer,Annette Thiel,Carina Matos,Christina Bruss,Sebastian Klobuch,K. Peter,K. Peter,Michael Kastenberger,Christian Bogdan,Ulrike Schleicher,Andreas Mackensen,Evelyn Ullrich,Stefan Fichtner-Feigl,Stefan Fichtner-Feigl,Rebecca Kesselring,Matthias Mack,Matthias Mack,Uwe Ritter,Maximilian Schmid,Maximilian Schmid,Christian U. Blank,Katja Dettmer,Peter J. Oefner,Petra Hoffmann,Petra Hoffmann,Stefan Walenta,E. K. Geissler,Jacques Pouysségur,Andreas Villunger,André Steven,Barbara Seliger,Stephan Schreml,Sebastian Haferkamp,Elisabeth Kohl,Sigrid Karrer,Mark Berneburg,Wolfgang Herr,Wolfgang Mueller-Klieser,Kathrin Renner,Kathrin Renner,Marina Kreutz,Marina Kreutz +45 more
TL;DR: It is shown that LDHA-associated lactic acid accumulation in melanomas inhibits tumor surveillance by T and NK cells, and is a potent inhibitor of function and survival of T andNK cells leading to tumor immune escape.