G
Gabriele Schoenhammer
Researcher at University Hospital Regensburg
Publications - 4
Citations - 957
Gabriele Schoenhammer is an academic researcher from University Hospital Regensburg. The author has contributed to research in topics: T cell & Medicine. The author has an hindex of 1, co-authored 2 publications receiving 592 citations.
Papers
More filters
Journal ArticleDOI
LDHA-Associated Lactic Acid Production Blunts Tumor Immunosurveillance by T and NK Cells.
Almut Brand,Katrin Singer,Gudrun E. Koehl,Marlene Kolitzus,Gabriele Schoenhammer,Annette Thiel,Carina Matos,Christina Bruss,Sebastian Klobuch,K. Peter,K. Peter,Michael Kastenberger,Christian Bogdan,Ulrike Schleicher,Andreas Mackensen,Evelyn Ullrich,Stefan Fichtner-Feigl,Stefan Fichtner-Feigl,Rebecca Kesselring,Matthias Mack,Matthias Mack,Uwe Ritter,Maximilian Schmid,Maximilian Schmid,Christian U. Blank,Katja Dettmer,Peter J. Oefner,Petra Hoffmann,Petra Hoffmann,Stefan Walenta,E. K. Geissler,Jacques Pouysségur,Andreas Villunger,André Steven,Barbara Seliger,Stephan Schreml,Sebastian Haferkamp,Elisabeth Kohl,Sigrid Karrer,Mark Berneburg,Wolfgang Herr,Wolfgang Mueller-Klieser,Kathrin Renner,Kathrin Renner,Marina Kreutz,Marina Kreutz +45 more
TL;DR: It is shown that LDHA-associated lactic acid accumulation in melanomas inhibits tumor surveillance by T and NK cells, and is a potent inhibitor of function and survival of T andNK cells leading to tumor immune escape.
Journal ArticleDOI
Anti-Thymocyte Globulin Treatment Augments 1,25-Dihydroxyvitamin D3 Serum Levels in Patients Undergoing Hematopoietic Stem Cell Transplantation
Carina Saraiva de Matos,Katrin Peter,Laura Weich,Alice Peuker,Gabriele Schoenhammer,Tobias Roider,Sakhila Ghimire,Nathalie Babl,Sonja Maria Decking,Martina Güllstorf,Nicolaus Kröger,Kathrin Hammon,Wolfgang Herr,Klaus Stark,Iris M. Heid,Kathrin Renner,Ernst Holler,Marina Kreutz +17 more
TL;DR: A cooperative effect of 25-hydroxyvitamin D3 and ATG in the regulation of 1,25-dihydroxyv Vitamin D3 production is demonstrated, suggesting that vitamin D3 supplementation may especially be important in patients receiving ATG for GvHD prophylaxis.
Journal ArticleDOI
Physiological levels of 25‐hydroxyvitamin D3 induce a suppressive CD4+ T cell phenotype not reflected in the epigenetic landscape
Carina Saraiva de Matos,Kathrin Renner,Alice Peuker,Gabriele Schoenhammer,Laura Schreiber,Christina Bruß,Ruediger Eder,Heiko Bruns,Cindy Flamann,Petra Hoffmann,Claudia Gebhard,Wolfgang Herr,Michael Rehli,Katrin Peter,Marina Kreutz +14 more
TL;DR: The data suggest that physiological levels of vitamin D3 act as potent modulator of human CD4+ T cells and autocrine or paracrine production of 1,25(OH)2D3 by T cells might be crucial for the local regulation of an adaptive immune response.
Posted ContentDOI
Metabolic stress and disease-stage specific basigin expression of peripheral blood immune cell subsets in COVID-19 patients
Peter J. Siska,Katrin Singer,Jana Klitzke,Nathalie Kauer,Sonja-Maria Decking,Christina Bruss,Carina Matos,Kristina Kolodova,Alic Peuker,Gabriele Schoenhammer,Johanna Raithel,Dirk Lunz,Bernhard M. Graf,Florian Geismann,Matthias Lubnow,Matthias Mack,Peter Hau,Christopher Bohr,Ralph Burkhardt,André Gessner,Bernd Salzberger,Frank Hanses,Florian Hitzenbichler,Daniel Heudobler,Florian Lueke,Tobias Pukrop,Wolfgang Herr,Daniel Wolff,Hendrik Poeck,Christoph Brochhausen,Petra Hoffmann,Michael Rehli,Marina Kreutz,Kathrin Renner +33 more
TL;DR: Basigin (CD147), but not established markers of T cell activation, was up-regulated on T cells from progressed COVID-19 patients and correlated with ROS accumulation, reflected in the transcriptome, and in vitro analyses confirmed the correlation and showed a down-regulation of ROS by dexamethasone treatment.