M
Marlon H. Cardoso
Researcher at Universidade Católica Dom Bosco
Publications - 65
Citations - 1632
Marlon H. Cardoso is an academic researcher from Universidade Católica Dom Bosco. The author has contributed to research in topics: Antimicrobial peptides & Antimicrobial. The author has an hindex of 18, co-authored 52 publications receiving 977 citations. Previous affiliations of Marlon H. Cardoso include University of Brasília & Universidade Católica de Brasília.
Papers
More filters
Journal ArticleDOI
Recent Advances in Anti-virulence Therapeutic Strategies With a Focus on Dismantling Bacterial Membrane Microdomains, Toxin Neutralization, Quorum-Sensing Interference and Biofilm Inhibition.
Osmel Fleitas Martínez,Osmel Fleitas Martínez,Marlon H. Cardoso,Marlon H. Cardoso,Marlon H. Cardoso,Suzana M. Ribeiro,Octavio L. Franco,Octavio L. Franco,Octavio L. Franco +8 more
TL;DR: This review presents some of the anti-virulence strategies that are currently being developed and will cover strategies focused on quench pathogen quorum sensing (QS) systems, disassemble of bacterial functional membrane microdomains (FMMs), disruption of biofilm formation and bacterial toxin neutralization.
Journal ArticleDOI
Synthetic antibiofilm peptides.
Cesar de la Fuente-Nunez,Marlon H. Cardoso,Elizabete de Souza Cândido,Octavio L. Franco,Robert E. W. Hancock +4 more
TL;DR: Recent developments in the new field of synthetic antibiofilm peptides are reviewed, including mechanistic insights, synergistic interactions with available antibiotics, and their potential as novel antimicrobials against persistent infections caused by biofilms are reviewed.
Journal ArticleDOI
Computer-Aided Design of Antimicrobial Peptides: Are We Generating Effective Drug Candidates?
Marlon H. Cardoso,Marlon H. Cardoso,Raquel Q. Orozco,Raquel Q. Orozco,Samilla B. Rezende,Gisele Regina Rodrigues,Karen G N Oshiro,Karen G N Oshiro,Elizabete de Souza Cândido,Elizabete de Souza Cândido,Octavio L. Franco +10 more
TL;DR: This review will focus on the main computational strategies that have generated AMPs with promising activities against pathogenic bacteria, as well as anti-infective potential in different animal models, including sepsis and cutaneous infections.
Journal ArticleDOI
The use of versatile plant antimicrobial peptides in agribusiness and human health.
Elizabete de Souza Cândido,Marlon H. Cardoso,Daniel Amaro Sousa,Juliane F.C. Viana,Nelson G. Oliveira-Júnior,Vívian de Jesus Miranda,Octavio L. Franco,Octavio L. Franco +7 more
TL;DR: This review will focus on the relevance of the structural-function relations of AMPs derived from plants and their proper use in applications for human health and agribusiness.
Journal ArticleDOI
Structure-function-guided exploration of the antimicrobial peptide polybia-CP identifies activity determinants and generates synthetic therapeutic candidates
Marcelo D. T. Torres,Marcelo D. T. Torres,Marcelo D. T. Torres,Cibele Nicolaski Pedron,Yasutomi Higashikuni,Yasutomi Higashikuni,Robin M. Kramer,Marlon H. Cardoso,Marlon H. Cardoso,Marlon H. Cardoso,Karen G N Oshiro,Octavio L. Franco,Octavio L. Franco,Octavio L. Franco,Pedro Ismael da Silva Junior,Fernanda Dias da Silva,Vani Xavier Oliveira Junior,Timothy K. Lu,Timothy K. Lu,Cesar de la Fuente-Nunez,Cesar de la Fuente-Nunez +20 more
TL;DR: It is demonstrated that, by tuning these physicochemical parameters, it is possible to design nontoxic synthetic peptides with enhanced sub-micromolar antimicrobial potency in vitro and anti-infective activity in vivo and to generate peptide antibiotics.