M
Marta Dabek
Researcher at Institut national de la recherche agronomique
Publications - 12
Citations - 1148
Marta Dabek is an academic researcher from Institut national de la recherche agronomique. The author has contributed to research in topics: Cathepsin G & Cancer. The author has an hindex of 7, co-authored 12 publications receiving 940 citations. Previous affiliations of Marta Dabek include Lund University.
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Journal ArticleDOI
Cancer-Associated Adipocytes Exhibit an Activated Phenotype and Contribute to Breast Cancer Invasion
Béatrice Dirat,Ludivine Bochet,Marta Dabek,Danièle Daviaud,Stéphanie Dauvillier,Bilal Majed,Yuan Yuan Wang,Aline Meulle,Bernard Salles,Sophie Le Gonidec,Ignacio Garrido,Ghislaine Escourrou,Philippe Valet,Catherine Muller +13 more
TL;DR: In vitro and in vivo evidence is provided that invasive cancer cells dramatically impact surrounding adipocytes and peritumoral adipocytes exhibit a modified phenotype and specific biological features sufficient to be named cancer-associated adipocytes (CAA); and CAAs modify the cancer cell characteristics/phenotype leading to a more aggressive behavior.
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Fecal proteases from diarrheic-IBS and ulcerative colitis patients exert opposite effect on visceral sensitivity in mice.
A Annaházi,Krisztina Gecse,Marta Dabek,Afifa Ait-Belgnaoui,András Rosztóczy,Richárd Róka,Tamás Molnár,Vassilia Theodorou,Tibor Wittmann,Lionel Bueno,Helene Eutamene +10 more
TL;DR: Elevated colonic luminal serine‐protease activity of diarrhea‐predominant IBS (IBS‐D) patients evokes a proteinase‐activated receptor (PAR)‐2‐mediated colonic hypersensitivity in mice, which contrasts with patients with IBD who exhibit visceral hypo‐ or normosensitivity to rectal distension.
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Fecal MMP-9: a new noninvasive differential diagnostic and activity marker in ulcerative colitis.
Anita Annaházi,Anita Annaházi,Tamás Molnár,Klaudia Farkas,András Rosztóczy,Ferenc Izbéki,Krisztina Gecse,Orsolya Inczefi,Ferenc Nagy,Imre Földesi,Mónika Szűcs,Marta Dabek,Laurent Ferrier,Vassilia Theodorou,Lionel Bueno,Tibor Wittmann,Richárd Róka +16 more
TL;DR: Fecal MMP-9 levels are highlighted as a useful tool in the differential diagnosis of diarrheic disorders and in the noninvasive evaluation of disease activity and mucosal healing in UC.
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Luminal Cathepsin G and Protease-Activated Receptor 4: A Duet Involved in Alterations of the Colonic Epithelial Barrier in Ulcerative Colitis
Marta Dabek,Laurent Ferrier,Richárd Róka,Krisztina Gecse,Anita Annaházi,Anita Annaházi,Jacques Moreau,Jean Escourrou,Christel Cartier,Gilles Chaumaz,Mathilde Leveque,Afifa Ait-Belgnaoui,Tibor Wittmann,Vassilia Theodorou,Lionel Bueno +14 more
TL;DR: Observations support that both Cat-G and PAR(4) play key roles in generating and/or amplifying relapses in UC and provide a rationale for the development of new therapeutic agents in the treatment of this disease.
Journal ArticleDOI
alpha-Ketoglutarate (AKG) absorption from pig intestine and plasma pharmacokinetics.
Marta Dabek,Danuta Kruszewska,Rafał Filip,A Hotowy,L Pierzynowski,A Wojtasz-Pajak,Sylwia Szymańczyk,J.L. Valverde Piedra,E Werpachowska,Stefan Pierzynowski +9 more
TL;DR: It is concluded that AKG was significantly better absorbed from the upper small intestine than from the distal sections and low pH, Fe(2+) and/or SO ions enhanced AKG absorption.