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Martha Skinner

Researcher at Boston University

Publications -  289
Citations -  17943

Martha Skinner is an academic researcher from Boston University. The author has contributed to research in topics: Amyloidosis & AL amyloidosis. The author has an hindex of 69, co-authored 289 publications receiving 16916 citations. Previous affiliations of Martha Skinner include Beth Israel Deaconess Medical Center & Veterans Health Administration.

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Journal ArticleDOI

Isolation and identification by sequence analysis of experimentally induced guinea pig amyloid fibrils

Martha Skinner, +3 more
- 01 Sep 1974 - 
TL;DR: A definite species specificity in A protein from human and guinea pig was identified on immunologic analysis and demonstrated a sequence homologous with that of A proteins fromhuman and monkey preparations but preceded by a 5-residue peptide which had an N-terminal histidine.
Journal Article

Soft tissue uptake of bone seeking radionuclide in amyloidosis

Robert A. Yood, +3 more
- 01 Sep 1981 - 
TL;DR: Amyloidosis should be considered in any patient with diffuse hepatic uptake or other soft tissue uptake of bone seeking radionuclides, and a mechanism for the abnormal uptake is postulated based on in vitro tissue analysis for calcium.
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Role of endocytic inhibitory drugs on internalization of amyloidogenic light chains by cardiac fibroblasts.

Grace Monis, +7 more
- 01 Dec 2006 - 
TL;DR: Results indicate that the cell internalizes light chain by a fluid phase endocytosis, which is then modified and ultimately compromises the cell.
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A simple screening test for variant transthyretins associated with familial transthyretin amyloidosis using isoelectric focusing

Lawreen H. Connors, +6 more
- 30 Sep 1998 - 
TL;DR: In sera from patients with ATTR who underwent liver transplantation, variant TTR was detected by IEF before, but not after, surgery, a simple, accurate, sensitive method is presented as a useful screening test for variant transthyretins associated with AT TR.
Journal ArticleDOI

Cellular response of cardiac fibroblasts to amyloidogenic light chains.

Vickery Trinkaus-Randall, +5 more
- 01 Jan 2005 - 
TL;DR: It is indicated that internalization of the light chains mediates the expression and localization of heparan sulfate proteoglycans inAmyloidoses and this study investigated the cellular response of primary cardiac fibroblasts to amyloidogenic light chains and determined the corresponding change in proteoglycanexpression and localization.