M
Martha Skinner
Researcher at Boston University
Publications - 289
Citations - 17943
Martha Skinner is an academic researcher from Boston University. The author has contributed to research in topics: Amyloidosis & AL amyloidosis. The author has an hindex of 69, co-authored 289 publications receiving 16916 citations. Previous affiliations of Martha Skinner include Beth Israel Deaconess Medical Center & Veterans Health Administration.
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Journal ArticleDOI
Endothelial dysfunction precedes C-fiber abnormalities in primary (AL) amyloidosis.
Martin Berghoff,Madeera Kathpal,Madeera Kathpal,Faisal Khan,Martha Skinner,Rodney H. Falk,Roy Freeman +6 more
TL;DR: Investigation of vascular and neural function in the cutaneous microcirculation of AL amyloidosis patients suggested that endothelial abnormalities precede and may contribute to the pathogenesis of the neuropathy associated with AL ameloidosis.
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P‐component of amyloid. Isolation from human serum by affinity chromatography
TL;DR: These studies compared similarities of tissue and plasma P-components and revealed the unique pentagonal ultrastructure of the plasma protein, which demonstrated immunologic identity and identical RF values of polyacrylamide disk gel electrophoresis.
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Characterization of P-component (AP) isolated from amyloidotic tissue: half-life studies of human and murine AP.
TL;DR: 'Tissue amyloid P- component is believed to be identical to the circulating serum P-component [SAP], a normal plasma glycoprotein,'.
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Diagnostic performance of amyloid A protein quantification in fat tissue of patients with clinical AA amyloidosis
Bouke P. C. Hazenberg,Johan Bijzet,Pieter Limburg,Martha Skinner,Philip N. Hawkins,Irena Butrimiene,Avi Livneh,Olga Lesnyak,Evgeney L Nasonov,Anna Filipowicz-Sosnowska,Ahmet Gül,Giampaolo Merlini,Piotr Wiland,Huri Ozdogan,Peter D. Gorevic,Hédi Ben Maïz,Merrill D. Benson,Haner Direskeneli,Kalevi Kaarela,D. Garceau,W. Hauck,Martin H. Van Rijswijk +21 more
TL;DR: Amyloid A protein quantification in fat tissue is a sensitive and specific method for detection of clinical AA amyloidosis and has potential for quantitative monitoring of tissue amyloids over time.
Journal ArticleDOI
The diflunisal trial : study accrual and drug tolerance
John L. Berk,Ole B. Suhr,Yoshiki Sekijima,Taro Yamashita,Michael A. Heneghan,Steven R. Zeldenrust,Yukio Ando,Shu-ichi Ikeda,Peter D. Gorevic,Giampaolo Merlini,Jeffrey W. Kelly,Martha Skinner,Alice Bisbee,Peter J. Dyck,Laura Obici +14 more
TL;DR: This is a randomized, placebo-controlled clinical trial to determine whether diflunisal, a well-known non-steroidal anti-inflammatory drug (NSAID) alters neurologic disease progression in FAP.