M
Martijn van Griensven
Researcher at Technische Universität München
Publications - 258
Citations - 11002
Martijn van Griensven is an academic researcher from Technische Universität München. The author has contributed to research in topics: Sepsis & Mesenchymal stem cell. The author has an hindex of 52, co-authored 240 publications receiving 9721 citations. Previous affiliations of Martijn van Griensven include Hannover Medical School & Mayo Clinic.
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Dose-dependent immunomodulatory effect of human stem cells from amniotic membrane: a comparison with human mesenchymal stem cells from adipose tissue.
Susanne Wolbank,Anja Peterbauer,Marc Fahrner,Simone Hennerbichler,Martijn van Griensven,Guido Stadler,Heinz Redl,Christian Gabriel +7 more
TL;DR: This study demonstrates, for the first time, contact- and dose-dependent immunosuppression of mesenchymal and epithelial amniotic SC populations, as well as of adipose tissue-derived SCs.
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The challenge of establishing preclinical models for segmental bone defect research.
Johannes C. Reichert,Siamak Saifzadeh,Siamak Saifzadeh,Martin Wullschleger,Devakara R. Epari,Michael A. Schütz,Georg N. Duda,Hanna Schell,Martijn van Griensven,Heinz Redl,Dietmar W. Hutmacher +10 more
TL;DR: The author expresses his opinion on methodologies to establish preclinical critically sized, segmental bone defect models used in past research with reference to surgical techniques, fixation methods and postoperative management focusing on tibial fracture and segmental defect models.
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Induced Hypothermia Does Not Harm Hemodynamics after Polytrauma: A Porcine Model
Matthias Weuster,Philipp Mommsen,Roman Pfeifer,Juliane Mohr,Juliane Mohr,Steffen Ruchholtz,Sascha Flohé,Matthias Fröhlich,Claudia Keibl,Andreas Seekamp,Martijn van Griensven,Martijn van Griensven,Ingo Witte +12 more
TL;DR: Therapeutic hypothermia revealed hints for tissue protective impact and might be a useful tool for intensive care after polytrauma, but the chosen length for therapeutichypothermia was too short.
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Five freely circulating miRNAs and bone tissue miRNAs are associated with osteoporotic fractures.
Claudine Seeliger,Katrin Karpinski,Alexander T. Haug,Helen Vester,Andreas Schmitt,Jan S. Bauer,Martijn van Griensven +6 more
TL;DR: An important role for several miRNAs are revealed in patients with osteoporotic patients and it is suggested that they may be used as biomarkers for diagnostic purposes and may be a target for treating bone loss and optimizing fracture healing in osteopOrotic patients.
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Major secondary surgery in blunt trauma patients and perioperative cytokine liberation: determination of the clinical relevance of biochemical markers.
H.-C. Pape,Martijn van Griensven,John Rice,Axel Gänsslen,Frank Hildebrand,Stefan Zech,Markus Winny,Ralf Lichtinghagen,Christian Krettek,Danny Sleeman,Ronald V. Maier,Carl J. Hauser,Frank R. Lewis +12 more
TL;DR: In patients with blunt multiple injuries undergoing primary temporary fixation of major fractures, the timing of secondary definitive surgery should be carefully selected, because it may act as a second hit phenomenon and cause a deterioration of the clinical status.