J
Johannes C. Reichert
Researcher at University of Würzburg
Publications - 71
Citations - 3664
Johannes C. Reichert is an academic researcher from University of Würzburg. The author has contributed to research in topics: Bone regeneration & Transplantation. The author has an hindex of 28, co-authored 63 publications receiving 3142 citations. Previous affiliations of Johannes C. Reichert include Queensland University of Technology & Charité.
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Journal ArticleDOI
How smart do biomaterials need to be? A translational science and clinical point of view ☆
Boris Michael Holzapfel,Johannes C. Reichert,Jan-Thorsten Schantz,Uwe Gbureck,Lars Rackwitz,Ulrich Nöth,Franz Jakob,Maximilian Rudert,Jürgen Groll,Dietmar W. Hutmacher +9 more
TL;DR: The purpose of the review is to assess state of the art and future perspectives of the so called "smart biomaterials" from a translational science and specifically clinical point of view and to filter out and discuss which biomedical advances and innovations help to achieve the objective to translate smart biomMaterials from bench to bedside.
Journal ArticleDOI
The challenge of establishing preclinical models for segmental bone defect research.
Johannes C. Reichert,Siamak Saifzadeh,Siamak Saifzadeh,Martin Wullschleger,Devakara R. Epari,Michael A. Schütz,Georg N. Duda,Hanna Schell,Martijn van Griensven,Heinz Redl,Dietmar W. Hutmacher +10 more
TL;DR: The author expresses his opinion on methodologies to establish preclinical critically sized, segmental bone defect models used in past research with reference to surgical techniques, fixation methods and postoperative management focusing on tibial fracture and segmental defect models.
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A Tissue Engineering Solution for Segmental Defect Regeneration in Load-Bearing Long Bones
Johannes C. Reichert,Amaia Cipitria,Devakara R. Epari,Siamak Saifzadeh,Pushpanjali Krishnakanth,Arne Berner,Arne Berner,Maria A. Woodruff,Hanna Schell,Manav Mehta,Michael Schuetz,Georg N. Duda,Dietmar W. Hutmacher +12 more
TL;DR: In this paper, the authors compared the gold standard autograft with biodegradable composite scaffolds consisting of medical-grade polycaprolactone and tricalcium phosphate combined with autologous bone marrow-derived mesenchymal stem cells (MSCs) or recombinant human bone morphogenetic protein 7 (rhBMP-7).
Journal ArticleDOI
Discrepancies between metabolic activity and DNA content as tool to assess cell proliferation in cancer research.
TL;DR: Test the metabolic activity of different cell types, human cancer cells and primary cells, over a time period of 4 days using AlamarBlue and the fluorometric assays CyQuant and PicoGreen to determine their DNA content and results show certain discrepancies in terms of over‐estimation of cell proliferation.
Journal ArticleDOI
Bone tissue engineering: from bench to bedside
Maria A. Woodruff,Claudia Lange,Johannes C. Reichert,Arne Berner,Fulen Chen,Peter Fratzl,Jan-Thorsten Schantz,Dietmar W. Hutmacher,Dietmar W. Hutmacher,Dietmar W. Hutmacher +9 more
TL;DR: The bench to bedside concept, the first clinical results and a detailed analysis of long-term bone regeneration studies in preclinical animal models are described, exploiting methods of micro- and nano analysis of biodegradable composite scaffolds.