M
Martin A. Mecchia
Researcher at Fundación Instituto Leloir
Publications - 21
Citations - 2162
Martin A. Mecchia is an academic researcher from Fundación Instituto Leloir. The author has contributed to research in topics: Arabidopsis thaliana & Arabidopsis. The author has an hindex of 14, co-authored 21 publications receiving 1786 citations. Previous affiliations of Martin A. Mecchia include University of Zurich & Facultad de Ciencias Exactas y Naturales.
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Journal ArticleDOI
Control of cell proliferation in Arabidopsis thaliana by microRNA miR396
Ramiro E. Rodriguez,Martin A. Mecchia,Juan M. Debernardi,Carla Schommer,Detlef Weigel,Javier F. Palatnik +5 more
TL;DR: It is shown that miR396 attenuates cell proliferation in developing leaves, through the repression of GRF activity and a decrease in the expression of cell cycle genes, and can regulate cell proliferation and the size of the meristem.
Journal Article
Control of cell proliferation in Arabidopsis thaliana by microRNA miR396
Ramiro E. Rodriguez,Martin A. Mecchia,Juan M. Debernardi,Carla Schommer,Detlef Weigel,Javier F. Palatnik +5 more
TL;DR: In this article, the role of microRNA miR396 in the coordination of cell proliferation in Arabidopsis leaves was investigated and shown to be a significant module in the regulation of plant proliferation in plants.
Journal ArticleDOI
Dynamics of chromatin accessibility and gene regulation by MADS-domain transcription factors in flower development.
Alice Pajoro,Pedro Madrigal,Jose M. Muiño,José Tomás Matus,Jian Jin,Martin A. Mecchia,Juan M. Debernardi,Javier F. Palatnik,Salma Balazadeh,Muhammad Arif,Diarmuid S. Ó’Maoiléidigh,Frank Wellmer,Paweł Krajewski,José Luis Riechmann,José Luis Riechmann,Gerco C. Angenent,Gerco C. Angenent,Kerstin Kaufmann,Kerstin Kaufmann +18 more
TL;DR: These findings indicate that different homeotic factors regulate partly overlapping, yet also distinctive sets of target genes in a partly stage-specific fashion and suggest that APETALA1 and SEPALLATA3 may modulate chromatin accessibility, thereby facilitating access of other transcriptional regulators to their target genes.
Journal ArticleDOI
Post-transcriptional control of GRF transcription factors by microRNA miR396 and GIF co-activator affects leaf size and longevity
Juan M. Debernardi,Martin A. Mecchia,Liesbeth Vercruyssen,Cezary Smaczniak,Kerstin Kaufmann,Dirk Inzé,Ramiro E. Rodriguez,Javier F. Palatnik +7 more
TL;DR: It is found that, in addition to the leaf size, the GRF system also affects the organ longevity and the functions of GRFs in leaf growth and senescence can be uncoupled, demonstrating that the miR396-GRF-GIF network impinges on different stages of leaf development.
Journal ArticleDOI
Functional specialization of the plant miR396 regulatory network through distinct microRNA-target interactions.
TL;DR: The results show that ancient miRNAs can regulate conserved targets with varied efficiency in different species, and it is proposed that they could acquire new targets whose control might also be biologically relevant.