M
Martin Bentz
Researcher at University of Ulm
Publications - 45
Citations - 6568
Martin Bentz is an academic researcher from University of Ulm. The author has contributed to research in topics: Comparative genomic hybridization & Fluorescence in situ hybridization. The author has an hindex of 28, co-authored 41 publications receiving 6338 citations. Previous affiliations of Martin Bentz include University of Würzburg.
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Journal ArticleDOI
Genomic Aberrations and Survival in Chronic Lymphocytic Leukemia
Hartmut Döhner,Stephan Stilgenbauer,Axel Benner,Elke Leupolt,Alexander Kröber,Lars Bullinger,Konstanze Döhner,Martin Bentz,Peter Lichter +8 more
TL;DR: Genomic aberrations in chronic lymphocytic leukemia are important independent predictors of disease progression and survival and have implications for the design of risk-adapted treatment strategies.
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Primary mediastinal (thymic) B-cell lymphoma is characterized by gains of chromosomal material including 9p and amplification of the REL gene
Stefan Joos,MI Otano-Joos,S Ziegler,Silke Brüderlein,S du Manoir,Martin Bentz,Peter Möller,P. Lichter +7 more
TL;DR: The characteristic pattern of chromosomal imbalances distinct from other B-cell lymphomas suggests a specific pathway of genetic changes associated with this lymphoma.
Journal Article
Genomic imbalances including amplification of the tyrosine kinase gene JAK2 in CD30+ Hodgkin cells
Stefan Joos,M Küpper,Sybille Ohl,F von Bonin,Gunhild Mechtersheimer,Martin Bentz,Peter Marynen,Peter Möller,Michael Pfreundschuh,Lorenz Trümper,P. Lichter +10 more
TL;DR: Several of the imbalances described, in particular a gain in chromosomal arm 9p that includes JAK2 amplification, are similar to the genomic changes detected in primary mediastinal B-cell lymphoma.
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Automated array-based genomic profiling in chronic lymphocytic leukemia: Development of a clinical tool and discovery of recurrent genomic alterations
Carsten Schwaenen,Michelle Nessling,Swen Wessendorf,Tatjana Salvi,Gunnar Wrobel,Bernhard Radlwimmer,Hans A. Kestler,Christian Haslinger,Stephan Stilgenbauer,Hartmut Döhner,Martin Bentz,Peter Lichter +11 more
TL;DR: A comprehensive DNA microarray dedicated to the automated analysis of recurrent genomic imbalances in B-CLL by array-based comparative genomic hybridization (matrix-CGH) revealed a high specificity and sensitivity that fulfils the criteria for application in clinical oncology.
Journal ArticleDOI
Disclosure of Candidate Genes in Acute Myeloid Leukemia With Complex Karyotypes Using Microarray-Based Molecular Characterization
Frank G. Rücker,Lars Bullinger,Carsten Schwaenen,Daniel B. Lipka,Swen Wessendorf,Stefan Fröhling,Martin Bentz,Simone Miller,Claudia Scholl,Richard F. Schlenk,Bernhard Radlwimmer,Hans A. Kestler,Jonathan R. Pollack,Peter Lichter,Konstanze Döhner,Hartmut Döhner +15 more
TL;DR: A large spectrum of genomic imbalances, including novel recurring changes in AML with complex karyotypes, was identified using array-CGH, allowing high-resolution genome-wide screening of genomicImbalances.