S
Swen Wessendorf
Researcher at University of Ulm
Publications - 44
Citations - 3925
Swen Wessendorf is an academic researcher from University of Ulm. The author has contributed to research in topics: Comparative genomic hybridization & Lymphoma. The author has an hindex of 26, co-authored 44 publications receiving 3613 citations.
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Journal ArticleDOI
A Biologic Definition of Burkitt's Lymphoma from Transcriptional and Genomic Profiling
Michael Hummel,Stefan Bentink,Hilmar Berger,Wolfram Klapper,Swen Wessendorf,Thomas F. E. Barth,Heinz Wolfram Bernd,Sergio Cogliatti,Judith Dierlamm,Alfred C. Feller,Martin-Leo Hansmann,Eugenia Haralambieva,Lana Harder,Dirk Hasenclever,Michael Kühn,Dido Lenze,Peter Lichter,José I. Martín-Subero,Peter Möller,Hans Konrad Müller-Hermelink,German Ott,Reza Parwaresch,Christiane Pott,Andreas Rosenwald,Maciej Rosolowski,Carsten Schwaenen,Benjamin Stürzenhofecker,Monika Szczepanowski,Heiko Trautmann,Hans Heinrich Wacker,Rainer Spang,Markus Loeffler,Lorenz Trümper,Harald Stein,Reiner Siebert +34 more
TL;DR: The molecular definition of Burkitt's lymphoma clarifies and extends the spectrum of the WHO criteria for Burkitt’s lymphoma.
Journal ArticleDOI
Automated array-based genomic profiling in chronic lymphocytic leukemia: Development of a clinical tool and discovery of recurrent genomic alterations
Carsten Schwaenen,Michelle Nessling,Swen Wessendorf,Tatjana Salvi,Gunnar Wrobel,Bernhard Radlwimmer,Hans A. Kestler,Christian Haslinger,Stephan Stilgenbauer,Hartmut Döhner,Martin Bentz,Peter Lichter +11 more
TL;DR: A comprehensive DNA microarray dedicated to the automated analysis of recurrent genomic imbalances in B-CLL by array-based comparative genomic hybridization (matrix-CGH) revealed a high specificity and sensitivity that fulfils the criteria for application in clinical oncology.
Journal ArticleDOI
Translocations activating IRF4 identify a subtype of germinal-center-derived B-cell lymphoma affecting predominantly children and young adults
Itziar Salaverria,Claudia Philipp,Ilske Oschlies,Christian W. Kohler,Markus Kreuz,Monika Szczepanowski,Birgit Burkhardt,Heiko Trautmann,Stefan Gesk,Mirosław Andrusiewicz,Mirosław Andrusiewicz,Hilmar Berger,Miriam Fey,Lana Harder,Dirk Hasenclever,Michael Hummel,Markus Loeffler,Friederike Mahn,Idoia Martin-Guerrero,Shoji Pellissery,Christiane Pott,Michael Pfreundschuh,Alfred Reiter,Julia Richter,Maciej Rosolowski,Carsten Schwaenen,Harald Stein,Lorenz Trümper,Swen Wessendorf,Rainer Spang,Ralf Küppers,Wolfram Klapper,Reiner Siebert +32 more
TL;DR: The results suggest IRF4 translocations to be primary alterations in a molecularly defined subset of GCB-derived lymphomas, suggesting that diversity in tumor biology might contribute to the age-dependent differences in prognosis of lymphoma.
Journal ArticleDOI
Disclosure of Candidate Genes in Acute Myeloid Leukemia With Complex Karyotypes Using Microarray-Based Molecular Characterization
Frank G. Rücker,Lars Bullinger,Carsten Schwaenen,Daniel B. Lipka,Swen Wessendorf,Stefan Fröhling,Martin Bentz,Simone Miller,Claudia Scholl,Richard F. Schlenk,Bernhard Radlwimmer,Hans A. Kestler,Jonathan R. Pollack,Peter Lichter,Konstanze Döhner,Hartmut Döhner +15 more
TL;DR: A large spectrum of genomic imbalances, including novel recurring changes in AML with complex karyotypes, was identified using array-CGH, allowing high-resolution genome-wide screening of genomicImbalances.
Journal Article
Microarray-based Copy Number and Expression Profiling in Dedifferentiated and Pleomorphic Liposarcoma
Björn Fritz,Falk Schubert,Gunnar Wrobel,Carsten Schwaenen,Swen Wessendorf,Michelle Nessling,Christian Korz,Ralf J. Rieker,Kate Montgomery,Raju Kucherlapati,Gunhild Mechtersheimer,Roland Eils,Stefan Joos,Peter Lichter +13 more
TL;DR: Application of dedicated clustering algorithms revealed that both tumor subtypes are clearly separated by the genomic profiles but only with a lesser power by the expression profiles, and genomic profiling appears to be more advantageous than RNA expression analysis.