M
Martin Macphee
Researcher at American Red Cross
Publications - 35
Citations - 1561
Martin Macphee is an academic researcher from American Red Cross. The author has contributed to research in topics: Fibrin & Hemostasis. The author has an hindex of 22, co-authored 35 publications receiving 1529 citations.
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Journal ArticleDOI
Effect of dry fibrin sealant dressings versus gauze packing on blood loss in grade V liver injuries in resuscitated swine.
John B. Holcomb,Anthony E. Pusateri,Richard A. Harris,Nathaniel C. Charles,Richard R. Gomez,James P. Cole,L. Dawson Beall,Vladislav Bayer,Martin Macphee,John R. Hess +9 more
TL;DR: In this model of grade V liver injury, blood loss with the DFSD was 51% of that observed with standard gauze packing (not statistically different), and initial survival data revealed no complications attributable to the fibrin dressing.
Journal ArticleDOI
Dry fibrin sealant dressings reduce blood loss, resuscitation volume, and improve survival in hypothermic coagulopathic swine with grade V liver injuries.
John B. Holcomb,John B. Holcomb,Anthony E. Pusateri,Richard A. Harris,Thomas J. Reid,Thomas J. Reid,L. Dawson Beall,John R. Hess,John R. Hess,Martin Macphee +9 more
TL;DR: In swine with a grade V liver injury complicated by a dilutional and hypothermic coagulopathy, DFSD provided simple, rapid hemorrhage control, decreased fluid requirements, and improved survival.
Journal ArticleDOI
Differential transforming abilities of non-secreted and secreted forms of human fibroblast growth factor-1.
R. Forough,Z Xi,Martin Macphee,Stanley Friedman,K A Engleka,T Sayers,R H Wiltrout,Thomas Maciag +7 more
TL;DR: The ability of FGF-1 to transform NIH 3T3 cells requires the function of a sp-directed secretory pathway and suggests that this pathway increases tumorigenicity in vivo.
Journal ArticleDOI
Efficacy of a Dry Fibrin Sealant Dressing for Hemorrhage Control After Ballistic Injury
John B. Holcomb,Martin Macphee,Stephen P. Hetz,Richard A. Harris,Anthony E. Pusateri,John R. Hess +5 more
TL;DR: The DFSD was superior to gauze in decreasing blood loss and maintaining blood pressure while retaining the simplicity of standard dressing application.
Journal ArticleDOI
Tumorigenic Transformation of Immortalized ECV Endothelial Cells by Cyclooxygenase-1 Overexpression
Kirsi Narko,Ari Ristimäki,Martin Macphee,Elizabeth Smith,Christian C. Haudenschild,Timothy Hla +5 more
TL;DR: Cox-1 overexpression in immortalized ECV endothelial cells results in nuclear localization of the polypeptide and tumorigenesis, suggesting a nonprostanoid function of Cox-1.