M
Martin Musilek
Publications - 40
Citations - 1725
Martin Musilek is an academic researcher. The author has contributed to research in topics: Neisseria meningitidis & Population. The author has an hindex of 17, co-authored 34 publications receiving 1646 citations.
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Predicted strain coverage of a meningococcal multicomponent vaccine (4CMenB) in Europe: a qualitative and quantitative assessment
Ulrich Vogel,Muhamed-Kheir Taha,Julio A. Vázquez,Jamie Findlow,Heike Claus,Paola Stefanelli,Dominique A. Caugant,Paula Kriz,Raquel Abad,Stefania Bambini,Anna Carannante,Ala Eddine Deghmane,Cecilia Fazio,Matthias Frosch,Giacomo Frosi,Stefanie Gilchrist,Marzia Monica Giuliani,Eva Hong,Morgan Ledroit,Pietro Giorgio Lovaglio,Jay Lucidarme,Martin Musilek,Alessandro Muzzi,Jan Oksnes,Fabio Rigat,Luca Orlandi,Maria Stella,Danielle Thompson,Mariagrazia Pizza,Rino Rappuoli,Davide Serruto,Maurizio Comanducci,Giuseppe Boccadifuoco,John J. Donnelly,Duccio Medini,Ray Borrow +35 more
TL;DR: MATS analysis showed that a multicomponent vaccine could protect against a substantial proportion of invasive MenB strains isolated in Europe, however, monitoring of antigen expression will be needed in the future.
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Distribution of Serogroups and Genotypes among Disease-Associated and Carried Isolates of Neisseria meningitidis from the Czech Republic, Greece, and Norway
Siamak Pour Yazdankhah,Paula Kriz,Georgina Tzanakaki,Jenny Kremastinou,Jitka Kalmusova,Martin Musilek,Torill Alvestad,Keith A. Jolley,Daniel J. Wilson,Noel D. McCarthy,Dominique A. Caugant,Dominique A. Caugant,Martin C. J. Maiden +12 more
TL;DR: Data robustly demonstrated differences in the distribution of meningococcal genotypes in disease and carrier isolates and among countries and indicated that differences in genotype diversity and pathogenicity exist between menedococcal clone complexes.
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Sequence Diversity of the Factor H Binding Protein Vaccine Candidate in Epidemiologically Relevant Strains of Serogroup B Neisseria meningitidis
Ellen Murphy,Lubomira Andrew,Kwok Leung Lee,Deborah A. Dilts,Nunez Lorna Del Pilar,Pamela Fink,Karita Ambrose,Ray Borrow,Jamie Findlow,Muhamed-Kheir Taha,Ala Eddine Deghmane,Paula Kriz,Martin Musilek,Jitka Kalmusova,Dominique A. Caugant,Torill Alvestad,Leonard W. Mayer,Claudio Tavares Sacchi,Claudio Tavares Sacchi,Xin Wang,Diana R. Martin,Anne von Gottberg,Mignon du Plessis,Keith P. Klugman,Annaliesa S. Anderson,Kathrin U. Jansen,Gary W. Zlotnick,Susan K. Hoiseth +27 more
TL;DR: An extensive survey and phylogenetic analysis of the diversity of fhbp genes and predicted protein sequences in invasive clinical isolates obtained in the period 2000-2006 underscores the importance of studying the distribution of the vaccine antigen itself rather than relying on common epidemiological surrogates such as MLST.
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Carried Meningococci in the Czech Republic: a Diverse Recombining Population
Keith A. Jolley,Jitka Kalmusova,Edward J. Feil,Sunetra Gupta,Martin Musilek,Paula Kriz,Martin C. J. Maiden +6 more
TL;DR: In this paper, molecular biology-based techniques were used to establish the genetic relationships of 156 meningococci isolated from healthy young adults in the Czech Republic during 1993 and none of the individuals sampled had known links to patients with invasive disease.
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Interaction of Neisseria meningitidis with the Components of the Blood-Brain Barrier Correlates with an Increased Expression of PilC
Bénédicte Pron,Muhamed-Kheir Taha,Caroline Rambaud,Jean-Christophe Fournet,Natacha Pattey,Jean-Paul Monnet,Martin Musilek,Jean-Luc Beretti,Xavier Nassif +8 more
TL;DR: Data suggest that PilC plays an important role in the crossing of the blood-brain barrier (BBB), likely through pilus-mediated adhesion.