M
Martin Reynders
Researcher at Ludwig Maximilian University of Munich
Publications - 34
Citations - 606
Martin Reynders is an academic researcher from Ludwig Maximilian University of Munich. The author has contributed to research in topics: Protein degradation & Chemistry. The author has an hindex of 6, co-authored 32 publications receiving 359 citations. Previous affiliations of Martin Reynders include New York University.
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Journal ArticleDOI
Photoswitchable Inhibitors of Microtubule Dynamics Optically Control Mitosis and Cell Death
Malgorzata Borowiak,Malgorzata Borowiak,Wallis Nahaboo,Martin Reynders,Katharina Nekolla,Pierre Jalinot,Jens Hasserodt,Markus Rehberg,Marie Delattre,Stefan Zahler,Angelika M. Vollmar,Dirk Trauner,Oliver Thorn-Seshold,Oliver Thorn-Seshold +13 more
TL;DR: The photostatins are introduced, inhibitors that can be switched on and off in vivo by visible light, to optically control microtubule dynamics and are promising as a new class of precision chemotherapeutics whose toxicity may be spatiotemporally constrained using light.
Journal ArticleDOI
PHOTACs enable optical control of protein degradation.
Martin Reynders,Martin Reynders,Bryan S. Matsuura,Marleen Bérouti,Marleen Bérouti,Daniele Simoneschi,Antonio Marzio,Michele Pagano,Dirk Trauner +8 more
TL;DR: The modular approach provides a method for the optical control of protein levels with photopharmacology and could lead to new types of precision therapeutics that avoid undesired systemic toxicity.
Journal ArticleDOI
Oxidative Approach Enables Efficient Access to Cyclic Azobenzenes.
Martin S. Maier,Martin S. Maier,Katharina Hüll,Katharina Hüll,Martin Reynders,Martin Reynders,Bryan S. Matsuura,Bryan S. Matsuura,Philipp Leippe,Tongil Ko,Lukas Schäffer,Dirk Trauner,Dirk Trauner +12 more
TL;DR: This work systematically explores substituent effects on the photoisomerization and thermal relaxation of diazocines to enable their incorporation into a wide variety of functional molecules, unlocking the full potential of these emerging photoswitches.
Journal ArticleDOI
Optical control of targeted protein degradation.
Martin Reynders,Dirk Trauner +1 more
TL;DR: A survey of the literature on light-responsive degraders can be found in this article, where the authors analyze the principles guiding the design of such systems, provide a survey, and discuss opportunities for further development.
Journal ArticleDOI
(2-Fluoro-2,2-dinitroethyl)-2,2,2-trinitroethylnitramine: A Possible High-Energy Dense Oxidizer
TL;DR: In this paper, the fluorine-containing polynitro energetic molecule (2-fluoro-2,2-dinitroethyl)-2-2-trinitronethylnitramine and the corresponding precursors were synthesized and investigated as potential high-energy dense oxidizers.