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Stefan Zahler
Researcher at Ludwig Maximilian University of Munich
Publications - 192
Citations - 8714
Stefan Zahler is an academic researcher from Ludwig Maximilian University of Munich. The author has contributed to research in topics: In vivo & Endothelial stem cell. The author has an hindex of 46, co-authored 188 publications receiving 7892 citations. Previous affiliations of Stefan Zahler include University of Regensburg.
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Journal ArticleDOI
An angiogenic role for the human peptide antibiotic LL-37/hCAP-18
Rembert Koczulla,Georges von Degenfeld,Christian Kupatt,Florian Krötz,Stefan Zahler,Torsten Gloe,Katja Issbrücker,Pia Unterberger,Mohamed Zaiou,Mohamed Zaiou,Corinna Lebherz,Alexander Karl,Philip Raake,Achim Pfosser,Peter Boekstegers,Ulrich Welsch,Pieter S. Hiemstra,Claus Vogelmeier,Richard L. Gallo,Richard L. Gallo,Matthias Clauss,Robert Bals,Robert Bals +22 more
TL;DR: It is demonstrated that LL-37/hCAP-18 is a multifunctional antimicrobial peptide with a central role in innate immunity by linking host defense and inflammation with angiogenesis and arteriogenesis.
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Intravascular tissue factor initiates coagulation via circulating microvesicles and platelets
Ingrid Müller,Antje Klocke,Meike Alex,Matthias Kotzsch,Thomas Luther,Eberhard Morgenstern,Susanne Zieseniss,Stefan Zahler,Klaus T. Preissner,Bernd Engelmann +9 more
TL;DR: The results introduce a new concept of TF‐mediated coagulation crucially dependent on TF associated with microvesicles and activated platelets, which principally enables the entire coagulated system to proceed on a restricted cell surface.
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Photoswitchable Inhibitors of Microtubule Dynamics Optically Control Mitosis and Cell Death
Malgorzata Borowiak,Malgorzata Borowiak,Wallis Nahaboo,Martin Reynders,Katharina Nekolla,Pierre Jalinot,Jens Hasserodt,Markus Rehberg,Marie Delattre,Stefan Zahler,Angelika M. Vollmar,Dirk Trauner,Oliver Thorn-Seshold,Oliver Thorn-Seshold +13 more
TL;DR: The photostatins are introduced, inhibitors that can be switched on and off in vivo by visible light, to optically control microtubule dynamics and are promising as a new class of precision chemotherapeutics whose toxicity may be spatiotemporally constrained using light.
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NAD(P)H oxidase-dependent platelet superoxide anion release increases platelet recruitment.
Florian Krötz,Hae Young Sohn,Torsten Gloe,Stefan Zahler,Tobias Riexinger,Thomas M. Schiele,Bernhard F. Becker,Karl Theisen,Volker Klauss,Ulrich Pohl +9 more
TL;DR: It is strongly suggested that collagen activation induces NAD(P)H oxidase-dependent O release in platelets, which in turn enhances availability of released ADP, resulting in increased platelet recruitment.
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Endothelial glycocalyx as an additional barrier determining extravasation of 6% hydroxyethyl starch or 5% albumin solutions in the coronary vascular bed.
Markus Rehm,Stefan Zahler,Michael Lötsch,Ulrich Welsch,Peter Conzen,Matthias Jacob,Bernhard F. Becker +6 more
TL;DR: The endothelial glycocalyx acts as a competent barrier for water and colloids and only after its destruction do changes in endothelial morphology (postischemic reperfusion or histamine application) become effective determinants of coronary extravasation.