M
Mary E. Wlodek
Researcher at University of Melbourne
Publications - 202
Citations - 4893
Mary E. Wlodek is an academic researcher from University of Melbourne. The author has contributed to research in topics: Offspring & Pregnancy. The author has an hindex of 35, co-authored 189 publications receiving 4251 citations. Previous affiliations of Mary E. Wlodek include University of Western Australia & St. Vincent's Institute of Medical Research.
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Journal ArticleDOI
Enhanced Uterine Artery Stiffness in Aged Pregnant Relaxin Mutant Mice Is Reversed with Exogenous Relaxin Treatment
Jonathan H. Gooi,Meghan Richardson,Maria Jelinic,Jane E. Girling,Mary E. Wlodek,Marianne Tare,Laura J. Parry +6 more
TL;DR: In conclusion, relaxin deficiency compromises uterine artery remodeling in older pregnant females, increasing the risk of pregnancy complications such as hypertension and intrauterine growth restriction.
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Cross-fostering and improved lactation ameliorates deficits in endocrine pancreatic morphology in growth-restricted adult male rat offspring
TL;DR: Lactation is highlighted as a critical period for intervention following prenatal restraint, whereby deficits in endocrine pancreatic mass and associated impaired in vivo insulin secretion can be ameliorated.
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Uteroplacental insufficiency programmes vascular dysfunction in non‐pregnant rats: compensatory adaptations in pregnancy
Marc Q. Mazzuca,Marianne Tare,Helena C. Parkington,Nicoleta Dragomir,Nicoleta Dragomir,Laura J. Parry,Mary E. Wlodek +6 more
TL;DR: Pregnancy was associated with increased outside and internal diameters in uterine and mesenteric arteries, but not renal and femoral arteries, and being born growth restricted did not alter this process, and arteries of growth restricted females adapted to changes.
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Growth restriction in the rat alters expression of metabolic genes during postnatal cardiac development in a sex-specific manner
Glenn D. Wadley,Glenn D. Wadley,Glenn K. McConell,Glenn K. McConell,Craig A. Goodman,Craig A. Goodman,Andrew L. Siebel,Kerryn T. Westcott,Mary E. Wlodek +8 more
TL;DR: During postnatal life male and female Control rats have similar patterns of expression for genes involved in mitochondrial biogenesis and glucose transport, however, following uteroplacental insufficiency these gene expression patterns diverge in males and females during early postnatalLife, with MnSOD gene expression reduced in later postnatallife.
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Parathyroid hormone-related protein(1-34) in gestational fluids and release from human gestational tissues
W. Farrugia,Patricia W. M. Ho,Gregory E. Rice,Jane M. Moseley,Michael Permezel,Mary E. Wlodek +5 more
TL;DR: This study unequivocally demonstrated that human gestational tissues release PTHrP and it was concluded that the main contributors to P THrP in amniotic fluid were the human fetal membranes, particularly amnion over placenta.