M
Mary E. Wlodek
Researcher at University of Melbourne
Publications - 202
Citations - 4893
Mary E. Wlodek is an academic researcher from University of Melbourne. The author has contributed to research in topics: Offspring & Pregnancy. The author has an hindex of 35, co-authored 189 publications receiving 4251 citations. Previous affiliations of Mary E. Wlodek include University of Western Australia & St. Vincent's Institute of Medical Research.
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Journal ArticleDOI
Normal lactational environment restores cardiomyocyte number after uteroplacental insufficiency: implications for the preterm neonate
M. Jane Black,Andrew L. Siebel,Andrew L. Siebel,Oksan Gezmish,Karen M. Moritz,Mary E. Wlodek +5 more
TL;DR: Findings reveal a critical developmental window, when cardiomyocytes are still proliferating, whereby improved neonatal nutrition has the capacity to restore cardiomeocyte number to normal levels, and are of particular relevance to the preterm infant who is born at a time whenCardiomyocyte number is immature and still dividing.
Journal ArticleDOI
Experimental and human evidence for Lipocalin-2 (Neutrophil Gelatinase-Associated Lipocalin NGAL ) in the development of cardiac hypertrophy and heart failure
Francine Z. Marques,Francine Z. Marques,Priscilla R. Prestes,Sean G. Byars,Scott C. Ritchie,Peter Würtz,Sheila K Patel,Scott A. Booth,Indrajeetsinh Rana,Yosuke Minoda,Stuart P. Berzins,Stuart P. Berzins,Claire L. Curl,Jimmy D. Bell,Bryan Wai,Piyush M Srivastava,Antti J. Kangas,Pasi Soininen,Pasi Soininen,Saku Ruohonen,Mika Kähönen,Terho Lehtimäki,Emma Raitoharju,Aki S. Havulinna,Markus Perola,Markus Perola,Olli T. Raitakari,Olli T. Raitakari,Veikko Salomaa,Mika Ala-Korpela,Johannes Kettunen,Johannes Kettunen,Johannes Kettunen,Maree A McGlynn,Jason Kelly,Mary E. Wlodek,Paul Lewandowski,Lea M.D. Delbridge,Louise M Burrell,Michael Inouye,Stephen B. Harrap,Fadi J. Charchar,Fadi J. Charchar,Fadi J. Charchar +43 more
TL;DR: Direct effects ofLCN2 on cardiomyocyte size and number and the consistent associations in experimental and human analyses reveal a central role for LCN2 in the ontogeny of cardiac hypertrophy and heart failure.
Journal ArticleDOI
Relaxin mediates uterine artery compliance during pregnancy and increases uterine blood flow
Lenka A. Vodstrcil,Marianne Tare,Jacqueline Novak,Nicoleta Dragomir,Rolando J. Ramirez,Mary E. Wlodek,Kirk P. Conrad,Laura J. Parry +7 more
TL;DR: A functional role for relaxin is demonstrated in mediating uterine artery compliance in pregnant rats, which may be necessary to maintain adequate uterine blood flow to the uterus and placenta.
Journal ArticleDOI
Plasma adrenocorticotropic hormone and cortisol and adrenal blood flow during sustained hypoxemia in fetal sheep.
J.R.G. Challis,J.R.G. Challis,B.S. Richardson,B.S. Richardson,Dan W. Rurak,Dan W. Rurak,Mary E. Wlodek,Mary E. Wlodek,J.E. Patrick,J.E. Patrick +9 more
TL;DR: The effect of sustained hypoxemia with progressive acidemia on pituitary-adrenal endocrine function (adrenocorticotropic hormone, cortisol) and on adrenal blood flow in fetal sheep is examined and it is concluded that the changes in fetal adrenocortiotropic hormone and cortisol seen in short-term hypoxia are reproduced during sustained hyp oxemia with acidemia.
Journal ArticleDOI
DNA Methyltransferase 1 Controls Nephron Progenitor Cell Renewal and Differentiation.
Nicola Wanner,Julia Vornweg,Alexander N. Combes,Sean M. Wilson,Julia Plappert,Gesa Rafflenbeul,Victor G. Puelles,Raza-Ur Rahman,Timur Liwinski,Saskia Lindner,Florian Grahammer,Oliver Kretz,Mary E. Wlodek,Tania Romano,Karen M. Moritz,Melanie Boerries,Hauke Busch,Stefan Bonn,Melissa H. Little,Wibke Bechtel-Walz,Tobias B. Huber +20 more
TL;DR: Findings establish DNA methylation as a key regulatory event of prenatal renal programming, which possibly represents a fundamental link between maternal nutritional factors during gestation and reduced nephron number.