M
Mary J. Warrell
Researcher at University of Oxford
Publications - 36
Citations - 2391
Mary J. Warrell is an academic researcher from University of Oxford. The author has contributed to research in topics: Rabies & Cerebral Malaria. The author has an hindex of 18, co-authored 36 publications receiving 2312 citations. Previous affiliations of Mary J. Warrell include Mahidol University & Liverpool School of Tropical Medicine.
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Journal ArticleDOI
Neurological manifestations of dengue infection.
Tom Solomon,Nguyen Minh Dung,David W. Vaughn,Rachel Kneen,Rachel Kneen,Le Thi Thu Thao,Boonyos Raengsakulrach,Ha Thi Loan,Nicholas P. J. Day,Nicholas P. J. Day,Jeremy Farrar,Jeremy Farrar,Khin S. A. Myint,Mary J. Warrell,William James,Amanda Nisalak,Nicholas J. White,Nicholas J. White +17 more
TL;DR: In dengue endemic areas patients with encephalitis and encephalopathy should be investigated for this infection, whether or not they have other features of the disease.
Journal ArticleDOI
Dexamethasone proves deleterious in cerebral malaria. A double-blind trial in 100 comatose patients.
David A. Warrell,Sornchai Looareesuwan,Mary J. Warrell,Prakit Kasemsarn,Ravivan Intaraprasert,Danai Bunnag,Harinasuta T +6 more
TL;DR: High-dose dexamethasone is deleterious in cerebral malaria and should no longer be used, and in a subgroup of 28 children six to 14 years old.
Journal ArticleDOI
The importance of anaemia in cerebral and uncomplicated falciparum malaria: role of complications, dyserythropoiesis and iron sequestration.
Rodney E. Phillips,Rodney E. Phillips,Rodney E. Phillips,Sornchai Looareesuwan,David A. Warrell,David A. Warrell,David A. Warrell,S H Lee,Juntra Karbwang,Mary J. Warrell,Mary J. Warrell,Mary J. Warrell,Nicholas J. White,Nicholas J. White,Nicholas J. White,C Swasdichai,D J Weatherall +16 more
TL;DR: Dyserythropoiesis and erythrophagocytosis were often present on admission but sometimes appeared after the parasitaemia had cleared and persisted for at least three weeks into convalescence, suggesting disturbances in iron metabolism and haemopoiedis are not completely explicable by red blood cell parasitisation.
Journal ArticleDOI
Quinine pharmacokinetics and toxicity in cerebral and uncomplicated falciparum malaria
Nicholas J. White,Sornchai Looareesuwan,David A. Warrell,Mary J. Warrell,Damnai Bunnag,Harinasuta T +5 more
TL;DR: The benefits of high plasma concentrations in the acute phase of this life-threatening disease appear to outweigh the risks, particularly in view of the increasing resistance of Plasmodium falciparum to quinine in Southeast Asia.
Journal ArticleDOI
Quinine loading dose in cerebral malaria.
Nicholas J. White,Sornchai Looareesuwan,David A. Warrell,Mary J. Warrell,Pornthep Chanthavanich,Danai Bunnag,Tranakchit Harinasuta +6 more
TL;DR: A loading dose of quinine proved a rapid and safe method of achieving plasma concentrations above the high minimum inhibitory concentrations for Plasmodium falciparum prevalent in Eastern Thailand.