M
Masaki Yasukawa
Researcher at Ehime University
Publications - 293
Citations - 10870
Masaki Yasukawa is an academic researcher from Ehime University. The author has contributed to research in topics: Cytotoxic T cell & Antigen. The author has an hindex of 54, co-authored 293 publications receiving 9998 citations. Previous affiliations of Masaki Yasukawa include Okayama University & Kanazawa University.
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Journal ArticleDOI
Development of functional human blood and immune systems in NOD/SCID/IL2 receptor γ chainnull mice
Fumihiko Ishikawa,Masaki Yasukawa,Bonnie L. Lyons,Shuro Yoshida,Toshihiro Miyamoto,Goichi Yoshimoto,Takeshi Watanabe,Koichi Akashi,Leonard D. Shultz,Mine Harada +9 more
TL;DR: A new nonobese diabetic/severe combined immunodeficient (NOD/SCID) mouse line harboring a complete null mutation of the common cytokine receptor γ chain efficiently supports development of functional human hemato-lymphopoiesis.
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The first identification and retrospective study of severe fever with thrombocytopenia syndrome in Japan
Toru Takahashi,Ken Maeda,Tadaki Suzuki,Aki Ishido,Toru Shigeoka,Takayuki Tominaga,Toshiaki Kamei,Masahiro Honda,Daisuke Ninomiya,Takenori Sakai,Takanori Senba,Shozo Kaneyuki,Shota Sakaguchi,Akira Satoh,Takanori Hosokawa,Yojiro Kawabe,Shintaro Kurihara,Koichi Izumikawa,Shigeru Kohno,Taichi Azuma,Koichiro Suemori,Masaki Yasukawa,Tetsuya Mizutani,Tsutomu Omatsu,Yukie Katayama,Masaharu Miyahara,Masahito Ijuin,Kazuko Doi,Masaru Okuda,Kazunori Umeki,Tomoya Saito,Kazuko Fukushima,Kensuke Nakajima,Tomoki Yoshikawa,Hideki Tani,Shuetsu Fukushi,Aiko Fukuma,Momoko Ogata,Masayuki Shimojima,Noriko Nakajima,Noriyo Nagata,Harutaka Katano,Hitomi Fukumoto,Yuko Sato,Hideki Hasegawa,Takuya Yamagishi,Kazunori Oishi,Ichiro Kurane,Shigeru Morikawa,Masayuki Saijo +49 more
TL;DR: This article describes the first identified patient with SFTS and a retrospective study on SFTS in Japan, which indicated that all of the Japanese SFTSV isolates formed a genotype independent to those from China.
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Nationwide survey of hemophagocytic lymphohistiocytosis in Japan.
Eiichi Ishii,Shouichi Ohga,Shinsaku Imashuku,Masaki Yasukawa,Hiroyuki Tsuda,Ikuo Miura,Ken Yamamoto,Hisanori Horiuchi,Kenzo Takada,Koichi Ohshima,Shigeo Nakamura,Naoko Kinukawa,Kazuo Oshimi,Keisei Kawa +13 more
TL;DR: Although this nationwide survey establishes the heterogeneous characteristics of HLH, the results should be useful in planning prospective studies to identify the most effective therapy for each HLH subtype.
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HLA class I-restricted lysis of leukemia cells by a CD8(+) cytotoxic T-lymphocyte clone specific for WT1 peptide.
TL;DR: This study established a CD8(+) cytotoxic T-lymphocyte (CTL) clone directed against a WT1-derived peptide and examined its immunologic actions on leukemia cells, suggesting that target antigen of TAK-1 on leukemia Cells is the naturally processed WT1 peptide in the context of HLA-A24.
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Generation of functional human T-cell subsets with HLA-restricted immune responses in HLA class I expressing NOD/SCID/IL2r gamma(null) humanized mice.
Leonard D. Shultz,Yoriko Saito,Yuho Najima,Satoshi Tanaka,Toshiki Ochi,Mariko Tomizawa,Takehiko Doi,Akiko Sone,Nahoko Suzuki,Hiroshi Fujiwara,Masaki Yasukawa,Fumihiko Ishikawa +11 more
TL;DR: The HLA-expressing humanized mouse with functional HLA -restricted T cells and consistent representation of rare T-cell subsets overcomes a major constraint in human immunology, and serves as a useful model for investigation of human immune responses against pathogens and for the development of therapeutic strategies against human diseases.