M
Masato Kasuga
Researcher at Kobe University
Publications - 506
Citations - 41710
Masato Kasuga is an academic researcher from Kobe University. The author has contributed to research in topics: Insulin receptor & Insulin. The author has an hindex of 96, co-authored 500 publications receiving 39782 citations. Previous affiliations of Masato Kasuga include Stanford University & Showa University.
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Journal ArticleDOI
Circadian variability of pharmacokinetics of 5-fluorouracil and CLOCK T3111C genetic polymorphism in patients with esophageal carcinoma.
Ikuya Miki,Takao Tamura,Tsutomu Nakamura,Hiroo Makimoto,Noriko Hamana,Hitoshi Uchiyama,Daisuke Shirasaka,Yoshinori Morita,Hiroyuki Yamada,Nobuo Aoyama,Toshiyuki Sakaeda,Katsuhiko Okumura,Masato Kasuga +12 more
TL;DR: Results revealed the elevation of plasma drug concentration and its reduced circadian variation during repetitive PVI of 5-FU during chemoradiotherapy and its administration schedule should be made in consideration of these phenomena.
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Downregulation of stomach cancer-associated protein tyrosine phosphatase-1 (SAP-1) in advanced human hepatocellular carcinoma.
Hidenobu Nagano,Tetsuya Noguchi,Kenjiro Inagaki,Seitetsu Yoon,Takashi Matozaki,Hiroshi Itoh,Masato Kasuga,Yoshitake Hayashi +7 more
TL;DR: Results indicate that SAP-1 expression is downregulated during the dedifferentiation of human HCC, and that this downregulation may play a causal role in disease progression.
Journal ArticleDOI
Effect of intrauterine undernutrition during late gestation on pancreatic beta cell mass
Tae Inoue,Yoshiaki Kido,Shun-ichiro Asahara,Tomokazu Matsuda,Yuki Shibutani,Maki Koyanagi,Masato Kasuga +6 more
TL;DR: The results indicate that the growth of pancreatic beta cells is insufficient in RG mice, and Pancreatic beta cell failure can easily develop as a consequence of insulin resistance.
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Association of the -112A>C polymorphism of the uncoupling protein 1 gene with insulin resistance in Japanese individuals with type 2 diabetes.
Keiko Fukuyama,Takeshi Ohara,Yushi Hirota,Kengo Maeda,Shin-ichi Kuno,Shin-ichi Kuno,Masako Zenibayashi,Tetsuya Teranishi,Kunichi Kouyama,Eiichi Maeda,Norihiro Sakamoto,Masato Kasuga +11 more
TL;DR: The results suggest that insulin resistance caused by the -112C allele influences the susceptibility to type 2 diabetes, and the genotypes of the two polymorphisms are determined.
Journal ArticleDOI
Subcellular trafficking kinetics of GLU4 mutated at the N- and C-terminal.
TL;DR: Wortmannin is shown to decrease glucose transport activity and cell-surface photolabelled transporters in a manner consistent with an inhibition of transporter recycling, and it is suggested that overexpression of transporter increases the proportion that are recycled in this way.