M
Mitsuru Hashiramoto
Researcher at Kawasaki Medical School
Publications - 43
Citations - 1941
Mitsuru Hashiramoto is an academic researcher from Kawasaki Medical School. The author has contributed to research in topics: Diabetes mellitus & Insulin receptor. The author has an hindex of 20, co-authored 43 publications receiving 1819 citations. Previous affiliations of Mitsuru Hashiramoto include Kobe University.
Papers
More filters
Journal ArticleDOI
International clinical harmonization of glycated hemoglobin in Japan: From Japan Diabetes Society to National Glycohemoglobin Standardization Program values.
Atsunori Kashiwagi,Masato Kasuga,Eiichi Araki,Yoshitomo Oka,Toshiaki Hanafusa,Hiroshi Ito,Makoto Tominaga,Shinichi Oikawa,Mitsuhiko Noda,Takahiko Kawamura,Tokio Sanke,Mitsuyoshi Namba,Mitsuru Hashiramoto,Takayuki Sasahara,Yoshihiko Nishio,Katsuhiko Kuwa,Kohjiro Ueki,Izumi Takei,Masao Umemoto,Masami Murakami,Minoru Yamakado,Yutaka Yatomi,Hatsumi Ohashi +22 more
TL;DR: The JDS extensively evaluated the usefulness and feasibility of more extended use of HbA1c in the diagnosis of diabetes based on Japanese epidemiological data, and then the ‘Report of the Committee on the Classification and Diagnostic Criteria of Diabetes Mellitus’ was published in the Journal of Diabetes Investigation5 and Diabetology International.
Journal ArticleDOI
The human glucagon-like peptide-1 analogue liraglutide preserves pancreatic beta cells via regulation of cell kinetics and suppression of oxidative and endoplasmic reticulum stress in a mouse model of diabetes
Masashi Shimoda,Yukiko Kanda,Sumiko Hamamoto,Kazuhito Tawaramoto,Mitsuru Hashiramoto,Michihiro Matsuki,Kohei Kaku +6 more
TL;DR: Liraglutide increases beta cell mass not only by directly regulating cell kinetics, but also by suppressing oxidative and ER stress, secondary to amelioration of glucolipotoxicity.
Journal ArticleDOI
Diabetes mellitus carrying a mutation in the mitochondrial tRNA(Leu(UUR)) gene.
Miyako Kishimoto,Mitsuru Hashiramoto,S Araki,Y. Ishida,Tsutomu Kazumi,F. Kanda,Masato Kasuga +6 more
TL;DR: It was established statistically that those with the 3243 mutation possess the following clinical characteristics; the age of diabetes onset is lower, they have lean body constitutions, and they are more likely to be treated with insulin than control subjects.
Journal ArticleDOI
Site-directed mutagenesis of GLUT1 in helix 7 residue 282 results in perturbation of exofacial ligand binding.
Mitsuru Hashiramoto,Takashi Kadowaki,A E Clark,A Muraoka,K Momomura,H. Sakura,K Tobe,Y Akanuma,Y. Yazaki,Geoffrey D. Holman +9 more
TL;DR: Of the 3 residues mutated in this study, only glutamine 282 substitution causes a major perturbation in function, and this is a specific and striking reduction in the affinity for the outside site-specific ligands ATB-BMPA and 4,6-O-ethylidene-D-glucose.
Journal ArticleDOI
Cleavage of vesicle-associated membrane protein (VAMP)-2 and cellubrevin on GLUT4-containing vesicles inhibits the translocation of GLUT4 in 3T3-L1 adipocytes
Yoshikazu Tamori,Mitsuru Hashiramoto,S Araki,Yoichi Kamata,Masami Takahashi,Shunji Kozaki,Masato Kasuga +6 more
TL;DR: It is concluded that the synaptobrevin isoforms are important components of the insulin-dependent translocation of GLUT4 to the cell surface in adipocytes.