Masatsugu Obuchi

TL;DR: There was continuous circulation in east and Southeast Asia via a region-wide network of temporally overlapping epidemics and that epidemics in the temperate regions were seeded from this network each year, suggesting that once A (H3N2) viruses leave E-SE Asia, they are unlikely to contribute to long-term viral evolution.

TL;DR: The World Health Organization Global Influenza Surveillance Network (WHO GISN) tracks and analyzes the evolution and epidemiology of influenza viruses for the primary purpose of vaccine strain selection and to improve the strain selection process through studies aimed at better understanding virus evolution and Epidemiology.

TL;DR: The functional analysis of the IL-8 gene revealed that both AP-1- and NF-kappaB factor-binding elements were involved in conferring the responsiveness to CMV, and electrophoretic mobility shift assays demonstrated that CMV induced the formation of NF- kappaB andAP-1 complexes.

TL;DR: Exposure of fibroblasts to IL-8 augmented both infectious virus production and replication of CMV, with concomitant increases in the levels of both the transcript of the CMV pp71 genome and the synthesis of theCMV late antigen.

TL;DR: Rec recombinant viruses between these strains of the two subgroups are used to demonstrate that the DA L coding region of DA strain is important for virus growth in J774-1 cells, and indicates that L* protein may play a critical role in the DA-induced restricted demyelinating infection by allowing growth in macrophages, a major site for virus persistence.