Massimo Barresi

TL;DR: It is revealed that arkypallidal neurons are part of a novel disynaptic feedback loop differentially recruited by the indirect or hyperdirect pathways and that broadcasts inhibitory control onto locomotion only when arky pallid neurons increase their activity.

TL;DR: The trigeminal, visceral and vestibular control of ARAS/LC activity may explain why these input signals affect sensorimotor and cognitive functions which are not directly related to their specific informational content and are effective in relieving the symptoms of some brain pathologies, thus prompting peripheral activation of these input systems as a complementary approach for the treatment of cognitive impairments and neurodegenerative disorders.

TL;DR: The present study indicates that the implant-prosthesis therapy, which reduces the unbalance of trigeminal proprioceptive afferents and the asymmetry in pupil’s size, may improve arousal, boosting performance in a complex sensorimotor task.

TL;DR: In this article, the authors show that activation of a receptor at different subcellular locations in the same neuronal circuit can determine distinct behaviors, such as antinociception and catalepsy.

TL;DR: Evidence is provided that fluoxetine induces sex specific changes in HDAC2 and mGlu2 expression in the DH of the spinal cord and in DRGs and a molecular explanation for the analgesic effects in female mice is suggested.