M
Masuzu Ueda
Researcher at Jichi Medical University
Publications - 9
Citations - 300
Masuzu Ueda is an academic researcher from Jichi Medical University. The author has contributed to research in topics: Multiple myeloma & Cell adhesion molecule. The author has an hindex of 6, co-authored 9 publications receiving 263 citations.
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Journal ArticleDOI
Bortezomib overcomes cell-adhesion-mediated drug resistance through downregulation of VLA-4 expression in multiple myeloma
Kaoru Noborio-Hatano,Jiro Kikuchi,Masaaki Takatoku,R Shimizu,Tomoaki Wada,Masuzu Ueda,Masaharu Nobuyoshi,Iekuni Oh,Sato Kazuya,Tatsuya Suzuki,Katsutoshi Ozaki,Masaki Mori,Tadashi Nagai,Kazuo Muroi,Yasuhiko Kano,Yusuke Furukawa,Keiya Ozawa +16 more
TL;DR: Functional screening using short hairpin RNA suggests that VLA-4 plays a critical role in CAM-DR of MM cells, and the combination of bortezomib with conventional anti-myeloma drugs may be effective in overcoming CAM- DR of MM.
Journal ArticleDOI
The bone marrow hematopoietic microenvironment is impaired in iron-overloaded mice.
TL;DR: Observations indicate that excess iron could affect hematopoietic improvement after iron chelation therapy in iron‐overloaded patients unfavorably, and to investigate how excess iron affects heMatopoiesis in vivo, iron‐ overloaded mice were generated and hematoietics parameters in these mice were examined.
Journal ArticleDOI
Rituximab plus 70% cyclophosphamide, doxorubicin, vincristine and prednisone for Japanese patients with diffuse large B-cell lymphoma aged 70 years and older.
Akiko Meguro,Katsutoshi Ozaki,Kazuya Sato,Iekuni Oh,Shin-ichiro Fujiwara,Rie Hosonuma,Miyuki Sasazaki,Yuji Kikuchi,Yuji Hirata,Chihiro Yamamoto,Mitsuyo Uesawa,Hiroyuki Kobayashi,Haruko Matsu,Hiroshi Okabe,Eisuke Uehara,Akinori Nishikawa,Raine Tatara,Kaoru Hatano,Chizuru Yamamoto,Tomohiro Matsuyama,Masaki Toshima,Masuzu Ueda,Ken Ohmine,Takahiro Suzuki,Masaki Mori,Tadashi Nagai,Kazuo Muroi,Keiya Ozawa +27 more
TL;DR: Three-year PFS with R-70%CHOP for patients aged 70 years and older was not significantly worse than that with full-dose R-CHop for younger patients, suggesting that R- 70% CHOP might be a reasonable choice for patients with DLBCL aged 70 year and older, especially for those with comorbidities.
Journal ArticleDOI
Renal failure caused by plasma cell infiltration in multiple myeloma
Shiho Hanawa,Tetsu Akimoto,Eisuke Uehara,Makoto Inoue,Toshimi Imai,Atsushi Kotoda,Hiromichi Yoshizawa,Tomohiro Matsuyama,Masuzu Ueda,Osamu Saito,Yoshitomo Hamano,Wako Yumura,Keiya Ozawa,Shigeaki Muto,Eiji Kusano +14 more
TL;DR: It is reasonable to consider that the infiltration of neoplastic plasma cells associated with local light chain depositions may result in irreversible renal injuries.
Journal ArticleDOI
Correlation between flow cytometric identification of CD33-positive cells and morphological evaluation of myeloblasts in bone marrow of patients with acute myeloblastic leukemia
Satoko Oka,Kazuo Muroi,Tomohiro Matsuyama,Kazuya Sato,Masuzu Ueda,Masaki Toshima,Takahiro Suzuki,Katsutoshi Ozaki,Masaki Mori,Takayuki Takubo,Tadashi Nagai,Toshiaki Hanafusa,Keiya Ozawa +12 more
TL;DR: The identification of CD33+ cells by FCM/CD45 is useful for the evaluation of bone marrow myeloblasts in AML.