M
Mathias Buttmann
Researcher at University of Würzburg
Publications - 6
Citations - 1526
Mathias Buttmann is an academic researcher from University of Würzburg. The author has contributed to research in topics: Optic neuritis & Neuromyelitis optica. The author has an hindex of 6, co-authored 6 publications receiving 1176 citations.
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Journal ArticleDOI
MOG-IgG in NMO and related disorders: a multicenter study of 50 patients. Part 2: Epidemiology, clinical presentation, radiological and laboratory features, treatment responses, and long-term outcome
Sven Jarius,Klemens Ruprecht,Ingo Kleiter,Nadja Borisow,Nasrin Asgari,Kalliopi Pitarokoili,Florence Pache,Oliver Stich,Lena-Alexandra Beume,Martin W. Hümmert,Marius Ringelstein,Corinna Trebst,Alexander Winkelmann,Alexander Schwarz,Mathias Buttmann,Hanna Zimmermann,Joseph Kuchling,Diego Franciotta,Marco Capobianco,Eberhard Siebert,Carsten Lukas,Mirjam Korporal-Kuhnke,Jürgen Haas,Kai Fechner,Alexander U. Brandt,Kathrin Schanda,Orhan Aktas,Friedemann Paul,Markus Reindl,Brigitte Wildemann +29 more
TL;DR: The predominantly relapsing and often severe disease course and the short median time to second attack support the use of prophylactic long-term treatments in patients with MOG-IgG-positive ON and/or myelitis; however, treatment failure leading to rapid accumulation of disability was noted in many patients as well as flare-ups after steroid withdrawal.
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MOG-IgG in NMO and related disorders: a multicenter study of 50 patients. Part 1: Frequency, syndrome specificity, influence of disease activity, long-term course, association with AQP4-IgG, and origin.
Sven Jarius,Klemens Ruprecht,Ingo Kleiter,Nadja Borisow,Nasrin Asgari,Kalliopi Pitarokoili,Florence Pache,Oliver Stich,Lena-Alexandra Beume,Martin W. Hümmert,Corinna Trebst,Marius Ringelstein,Orhan Aktas,Alexander Winkelmann,Mathias Buttmann,Alexander Schwarz,Hanna Zimmermann,Alexander U. Brandt,Diego Franciotta,Marco Capobianco,Joseph Kuchling,Jürgen Haas,Mirjam Korporal-Kuhnke,Soeren Thue Lillevang,Kai Fechner,Kathrin Schanda,Friedemann Paul,Brigitte Wildemann,Markus Reindl +28 more
TL;DR: This is the largest cohort studied for IgG to human full-length MOG by means of an up-to-date CBA and finds MOG-IgG is present in a substantial subset of patients with ON and/or myelitis, but not in classical MS.
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MOG-IgG in NMO and related disorders: a multicenter study of 50 patients. Part 4: Afferent visual system damage after optic neuritis in MOG-IgG-seropositive versus AQP4-IgG-seropositive patients
Florence Pache,Hanna Zimmermann,Janine Mikolajczak,Sophie Schumacher,Anna Lacheta,Frederike C. Oertel,Judith Bellmann-Strobl,Judith Bellmann-Strobl,Sven Jarius,Brigitte Wildemann,Markus Reindl,Amy Waldman,Kerstin Soelberg,Nasrin Asgari,Marius Ringelstein,Orhan Aktas,Nikolai Gross,Mathias Buttmann,Thomas Ach,Klemens Ruprecht,Friedemann Paul,Friedemann Paul,Alexander U. Brandt +22 more
TL;DR: Retinal neuro-axonal damage and visual impairment after ON in MOG-IgG-positive patients are as severe as in AQP4-IGG- positive NMOSD patients.
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MOG-IgG in NMO and related disorders: a multicenter study of 50 patients. Part 3: Brainstem involvement - frequency, presentation and outcome.
Sven Jarius,Ingo Kleiter,Klemens Ruprecht,Nasrin Asgari,Kalliopi Pitarokoili,Nadja Borisow,Martin W. Hümmert,Corinna Trebst,Florence Pache,Alexander Winkelmann,Lena Beume,Marius Ringelstein,Oliver Stich,Orhan Aktas,Mirjam Korporal-Kuhnke,Alexander Schwarz,Carsten Lukas,Jürgen Haas,Kai Fechner,Mathias Buttmann,Judith Bellmann-Strobl,Hanna Zimmermann,Alexander U. Brandt,Diego Franciotta,Kathrin Schanda,Friedemann Paul,Markus Reindl,Brigitte Wildemann +27 more
TL;DR: Brainstem involvement is present in around one third of MOG-IgG-positive patients with ON and/or myelitis, and is associated with a more aggressive general disease course.
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Malignancies after mitoxantrone for multiple sclerosis A retrospective cohort study
TL;DR: While the overall incidence of malignancies was only mildly increased, the risk of leukemia and colorectal cancer was heightened, and posttherapy colonoscopy could become advisable if confirmed.