O
Oliver Stich
Researcher at University of Freiburg
Publications - 79
Citations - 3042
Oliver Stich is an academic researcher from University of Freiburg. The author has contributed to research in topics: Multiple sclerosis & Myelitis. The author has an hindex of 22, co-authored 77 publications receiving 2379 citations. Previous affiliations of Oliver Stich include University Medical Center Freiburg.
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Journal ArticleDOI
MOG-IgG in NMO and related disorders: a multicenter study of 50 patients. Part 2: Epidemiology, clinical presentation, radiological and laboratory features, treatment responses, and long-term outcome
Sven Jarius,Klemens Ruprecht,Ingo Kleiter,Nadja Borisow,Nasrin Asgari,Kalliopi Pitarokoili,Florence Pache,Oliver Stich,Lena-Alexandra Beume,Martin W. Hümmert,Marius Ringelstein,Corinna Trebst,Alexander Winkelmann,Alexander Schwarz,Mathias Buttmann,Hanna Zimmermann,Joseph Kuchling,Diego Franciotta,Marco Capobianco,Eberhard Siebert,Carsten Lukas,Mirjam Korporal-Kuhnke,Jürgen Haas,Kai Fechner,Alexander U. Brandt,Kathrin Schanda,Orhan Aktas,Friedemann Paul,Markus Reindl,Brigitte Wildemann +29 more
TL;DR: The predominantly relapsing and often severe disease course and the short median time to second attack support the use of prophylactic long-term treatments in patients with MOG-IgG-positive ON and/or myelitis; however, treatment failure leading to rapid accumulation of disability was noted in many patients as well as flare-ups after steroid withdrawal.
Journal ArticleDOI
MOG-IgG in NMO and related disorders: a multicenter study of 50 patients. Part 1: Frequency, syndrome specificity, influence of disease activity, long-term course, association with AQP4-IgG, and origin.
Sven Jarius,Klemens Ruprecht,Ingo Kleiter,Nadja Borisow,Nasrin Asgari,Kalliopi Pitarokoili,Florence Pache,Oliver Stich,Lena-Alexandra Beume,Martin W. Hümmert,Corinna Trebst,Marius Ringelstein,Orhan Aktas,Alexander Winkelmann,Mathias Buttmann,Alexander Schwarz,Hanna Zimmermann,Alexander U. Brandt,Diego Franciotta,Marco Capobianco,Joseph Kuchling,Jürgen Haas,Mirjam Korporal-Kuhnke,Soeren Thue Lillevang,Kai Fechner,Kathrin Schanda,Friedemann Paul,Brigitte Wildemann,Markus Reindl +28 more
TL;DR: This is the largest cohort studied for IgG to human full-length MOG by means of an up-to-date CBA and finds MOG-IgG is present in a substantial subset of patients with ON and/or myelitis, but not in classical MS.
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Cerebrospinal fluid findings in aquaporin-4 antibody positive neuromyelitis optica: results from 211 lumbar punctures.
Sven Jarius,Friedemann Paul,Diego Franciotta,Klemens Ruprecht,Marius Ringelstein,Roberto Bergamaschi,Paulus S. Rommer,Ingo Kleiter,Oliver Stich,Reinhard Reuss,Sebastian Rauer,Uwe K. Zettl,Klaus-Peter Wandinger,Arthur Melms,Orhan Aktas,Wolfgang Kristoferitsch,Brigitte Wildemann +16 more
TL;DR: AQP4-Ab positive NMOSD is characterized by CSF features that are distinct from those in MS, and these findings are important for the differential diagnosis of MS andNMOSD and add to the understanding of the immunopathogenesis of this devastating condition.
Journal ArticleDOI
MOG-IgG in NMO and related disorders: a multicenter study of 50 patients. Part 3: Brainstem involvement - frequency, presentation and outcome.
Sven Jarius,Ingo Kleiter,Klemens Ruprecht,Nasrin Asgari,Kalliopi Pitarokoili,Nadja Borisow,Martin W. Hümmert,Corinna Trebst,Florence Pache,Alexander Winkelmann,Lena Beume,Marius Ringelstein,Oliver Stich,Orhan Aktas,Mirjam Korporal-Kuhnke,Alexander Schwarz,Carsten Lukas,Jürgen Haas,Kai Fechner,Mathias Buttmann,Judith Bellmann-Strobl,Hanna Zimmermann,Alexander U. Brandt,Diego Franciotta,Kathrin Schanda,Friedemann Paul,Markus Reindl,Brigitte Wildemann +27 more
TL;DR: Brainstem involvement is present in around one third of MOG-IgG-positive patients with ON and/or myelitis, and is associated with a more aggressive general disease course.
Journal ArticleDOI
Immunological findings in psychotic syndromes: a tertiary care hospital's CSF sample of 180 patients.
Dominique Endres,Evgeniy Perlov,Annette Baumgartner,Tilman Hottenrott,Rick Dersch,Oliver Stich,Ludger Tebartz van Elst +6 more
TL;DR: The main finding of this study was the high prevalence of CSF and autoantibody abnormalities in 54.4% of psychotic patients and the efficacy of immunomodulatory therapies.