M
Mathilde Hunault-Berger
Researcher at University of Angers
Publications - 84
Citations - 1991
Mathilde Hunault-Berger is an academic researcher from University of Angers. The author has contributed to research in topics: Medicine & Myeloid leukemia. The author has an hindex of 17, co-authored 70 publications receiving 1733 citations. Previous affiliations of Mathilde Hunault-Berger include Curie Institute & University of Nantes.
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Journal ArticleDOI
Essential role for the p110δ isoform in phosphoinositide 3-kinase activation and cell proliferation in acute myeloid leukemia
Pierre Sujobert,Valérie Bardet,Pascale Cornillet-Lefebvre,Joel S. Hayflick,Nolwen Prie,Frederic Verdier,Bart Vanhaesebroeck,Odile Muller,Florence Pesce,Norbert Ifrah,Mathilde Hunault-Berger,Christian Berthou,Bruno Villemagne,Eric Jourdan,Bruno Audhuy,Eric Solary,Brigitte Witz,Jean Luc Harousseau,Chantal Himberlin,Thierry Lamy,Bruno Lioure,Jean-Yves Cahn,François Dreyfus,Patrick Mayeux,Catherine Lacombe,Didier Bouscary +25 more
TL;DR: It is shown that the p110δ isoform of PI3K is consistently expressed at a high level in blast cells from AML, in contrast to the other class I isoforms, the expression of which was very variable among patients.
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TET2 mutation is an independent favorable prognostic factor in myelodysplastic syndromes (MDSs).
Olivier Kosmider,Véronique Gelsi-Boyer,Meyling Cheok,Sophie Grabar,Véronique Della-Valle,Françoise Picard,Franck Viguié,Bruno Quesnel,Odile Beyne-Rauzy,Eric Solary,Norbert Vey,Mathilde Hunault-Berger,Pierre Fenaux,Véronique Mansat-De Mas,Eric Delabesse,Philippe Guardiola,Catherine Lacombe,William Vainchenker,Claude Preudhomme,François Dreyfus,Olivier A. Bernard,Daniel Birnbaum,Michaela Fontenay +22 more
TL;DR: Results indicate that TET2 mutations observed in approximately 20% of patients, irrespective of the World Health Organization or French-American-British subtype, represent a molecular marker for good prognosis in MDS.
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Mutations of IDH1 and IDH2 genes in early and accelerated phases of myelodysplastic syndromes and MDS/myeloproliferative neoplasms.
Olivier Kosmider,Véronique Gelsi-Boyer,L Slama,Francois Dreyfus,Odile Beyne-Rauzy,Bruno Quesnel,Mathilde Hunault-Berger,Borhane Slama,Norbert Vey,Catherine Lacombe,Eric Solary,David Jérémie Birnbaum,Olivier A. Bernard,Michaela Fontenay +13 more
TL;DR: Mutations of IDH1 and IDH2 genes in early and accelerated phases of myelodysplastic syndromes and MDS/myeloproliferative neoplasms are confirmed.
Journal ArticleDOI
Changes in antithrombin and fibrinogen levels during induction chemotherapy with L-asparaginase in adult patients with acute lymphoblastic leukemia or lymphoblastic lymphoma. Use of supportive coagulation therapy and clinical outcome: the CAPELAL study
Mathilde Hunault-Berger,Patrice Chevallier,Martine Delain,Claude-Eric Bulabois,Serge Bologna,Marc Bernard,Ingrid Lafon,Jérôme Cornillon,Abdallah Maakaroun,Alexandra Tizon,Bruno Padrazzi,Norbert Ifrah,Yves Gruel +12 more
TL;DR: This retrospective study suggests that antithrombin concentrates may have a beneficial effect on the outcome of adults treated for acute lymphoblastic leukemia with L-asparaginase; prospective studies are essential to confirm this hypothesis.
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Tumour lysis syndrome and acute kidney injury in high-risk haematology patients in the rasburicase era. A prospective multicentre study from the Groupe de Recherche en Réanimation Respiratoire et Onco-Hématologique.
Michael Darmon,François Vincent,Laurent Camous,Emmanuel Canet,Caroline Bonmati,Thorsten Braun,Denis Caillot,Jérôme Cornillon,Sophie Dimicoli,Anne Etienne,Lionel Galicier,Alice Garnier,Stephane Girault,Mathilde Hunault-Berger,Jean-Pierre Marolleau,Philippe Moreau,Emmanuel Raffoux,Christian Recher,Anne Thiebaud,Catherine Thieblemont,Elie Azoulay +20 more
TL;DR: TLS was associated with increased mortality, indicating a need for interventional studies aimed at decreasing early TLS‐related deaths in this setting, and there should be further research into this setting.