M
Matthew Lacorcia
Researcher at Technische Universität München
Publications - 8
Citations - 70
Matthew Lacorcia is an academic researcher from Technische Universität München. The author has contributed to research in topics: Immune system & Immunology. The author has an hindex of 3, co-authored 5 publications receiving 33 citations.
Papers
More filters
Journal ArticleDOI
Host immune responses during Taenia solium Neurocysticercosis infection and treatment.
Ulrich Fabien Prodjinotho,Jakobo Lema,Matthew Lacorcia,Veronika Schmidt,Veronika Schmidt,Nermina Vejzagic,C.S. Sikasunge,Bernard Ngowi,Bernard Ngowi,Andrea Sylvia Winkler,Andrea Sylvia Winkler,Clarissa Prazeres da Costa +11 more
TL;DR: The immunological parameters associated with NCC in people living with HIV/AIDS and treatments are discussed, and open questions to understand the role of the immune system and its impact in this intriguing host–parasite crosstalk are proposed.
Journal ArticleDOI
Maternal Schistosomiasis: Immunomodulatory Effects With Lasting Impact on Allergy and Vaccine Responses
TL;DR: This review explores how maternal schistosome infection could drive changes in immune system development of offspring and how this may lead to identifying factors involved in altering responses to vaccination as well as manifestations of immune disorders including allergy.
Journal ArticleDOI
Placental gene expression and antibody levels of mother-neonate pairs reveal an enhanced risk for inflammation in a helminth endemic country.
Esther Ludwig,Jutta Harder,Matthew Lacorcia,Yabo Josiane Honkpehedji,Odilon Nouatin,Govert J. van Dam,Paul L. A. M. Corstjens,Erliyani Sartono,Meral Esen,Silvia M. Lobmaier,Ayola A. Adegnika,Clarissa Prazeres da Costa +11 more
TL;DR: Exposure in utero to different environments alters placental gene expression and thus possibly plays a role in the development and modulation of the immune system of the offspring, demonstrating that exposure to environmental factors can modify the development of allergies later in life.
Journal ArticleDOI
Fetomaternal immune cross talk modifies T-cell priming through sustained changes to DC function.
Matthew Lacorcia,Sonakshi Bhattacharjee,Kristina Laubhahn,Kristina Laubhahn,Fahd Alhamdan,Marija Ram,Andreas Muschaweckh,Daniel P. Potaczek,Anna D. Kosinska,Holger Garn,Ulrike Protzer,Harald Renz,Clarissa Prazeres da Costa +12 more
TL;DR: In this paper, a model of chronic maternal schistosomiasis infection was combined with a thorough analysis of subsequent offspring immune responses to allergy and vaccination models, including viral challenge and steady-state changes to immune cell compartments.
Journal ArticleDOI
Helminthic dehydrogenase drives PGE2 and IL‐10 production in monocytes to potentiate Treg induction
Ulrich Fabien Prodjinotho,Vitka Gres,Fiona Henkel,Matthew Lacorcia,Ramona Dandl,Martin Haslbeck,Veronika Schmidt,Andrea Sylvia Winkler,C.S. Sikasunge,Per-Johan Jakobsson,Philipp Henneke,Julia Esser-von Bieren,Clarissa Prazeres da Costa +12 more
TL;DR: It is shown that glutamate dehydrogenase from viable cysts instructs tolerogenic monocytes to release IL‐10 and the lipid mediator PGE2, and Harnessing the P GE2‐IL‐10 axis and targeting TGF‐ß signaling may offer an important therapeutic strategy in inflammatory epilepsy and NCC.