M
Meral Esen
Researcher at University of Tübingen
Publications - 85
Citations - 3420
Meral Esen is an academic researcher from University of Tübingen. The author has contributed to research in topics: Malaria & Plasmodium falciparum. The author has an hindex of 27, co-authored 71 publications receiving 2605 citations. Previous affiliations of Meral Esen include Albert Schweitzer Hospital.
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Journal ArticleDOI
Sterile protection against human malaria by chemoattenuated PfSPZ vaccine
Benjamin Mordmüller,Güzin Surat,Heimo Lagler,Heimo Lagler,Sumana Chakravarty,Andrew S. Ishizuka,Albert Lalremruata,Markus Gmeiner,Joseph J. Campo,Meral Esen,Adam Ruben,Jana Held,Carlos Lamsfus Calle,Juliana Boex Mengue,Tamirat Gebru,Javier Ibáñez,Mihály Sulyok,Eric R. James,Peter F. Billingsley,Natasha Kc,Anita Manoj,Tooba Murshedkar,Anusha Gunasekera,Abraham G. Eappen,Tao Li,Richard E. Stafford,Minglin Li,Phil Felgner,Robert A. Seder,Thomas L. Richie,B. Kim Lee Sim,Stephen L. Hoffman,Peter G. Kremsner +32 more
TL;DR: PfSPZ-CVac is a highly efficacious vaccine candidate that could be used for combination mass drug administration and a mass vaccination program approach to eliminate malaria from geographically defined areas when able to optimize the immunization regimen.
Journal ArticleDOI
Atypical and classical memory B cells produce Plasmodium falciparum neutralizing antibodies
Matthias F Muellenbeck,Beatrix Ueberheide,Borko Amulic,Alexandra Epp,David Fenyö,Christian E. Busse,Meral Esen,Michael Theisen,Benjamin Mordmüller,Hedda Wardemann +9 more
TL;DR: Plasmodium falciparum infection leads to the development of protective classical and atypical memory B cell antibody responses.
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Respiratory Syncytial Virus and Other Respiratory Viral Infections in Older Adults With Moderate to Severe Influenza-like Illness
Ann R. Falsey,Janet E. McElhaney,Jiri Beran,Gerrit A van Essen,Xavier Duval,Meral Esen,Florence Galtier,Pierre Gervais,Shinn-Jang Hwang,Peter G. Kremsner,Odile Launay,Geert Leroux-Roels,Shelly A. McNeil,Andrzej Nowakowski,Jan Hendrik Richardus,Guillermo M. Ruiz-Palacios,Suzanne St Rose,Jeanne-Marie Devaster,Lidia Oostvogels,Serge Durviaux,Sylvia Taylor +20 more
TL;DR: This first global study providing data on RSV disease in ≥65 year-olds confirms that RSV is an important respiratory pathogen in the elderly and preventative measures such as vaccination could decrease severe respiratory illnesses and complications inThe elderly.
Journal ArticleDOI
Mechanisms of Staphylococcus aureus induced apoptosis of human endothelial cells.
Meral Esen,B. Schreiner,Verena Jendrossek,Florian Lang,Klaus Fassbender,Heike Grassmé,Erich Gulbins +6 more
TL;DR: Staphylococcus aureus plays an important role in sepsis, pneumonia and wound infections and it is demonstrated that infection with several S. a Aureus strains results in apoptosis of human endothelial cells.
Journal ArticleDOI
The IκB Kinase Complex and NF-κB Act as Master Regulators of Lipopolysaccharide-Induced Gene Expression and Control Subordinate Activation of AP-1
Daniel Krappmann,Elmar Wegener,Yoshiaki Sunami,Meral Esen,Andreas Thiel,Benjamin Mordmüller,Claus Scheidereit +6 more
TL;DR: It is illustrated that NF-κB orchestrates immediate-early effects of LPS signaling and controls secondary AP-1 activation to mount an appropriate biological response.