Matthew Patrick

TL;DR: Pat et al. as discussed by the authors constructed a consensus mapping between ICD-10 codes and ORPHA codes for rare diseases, then identified individuals with each rare condition in the UK Biobank, and investigated their age at recruitment, sex bias, and comorbidity distributions.

TL;DR: In this paper , the authors conducted a two-stage association study and meta-analysis with 544 kidney biopsy-defined patients with acute tubulointerstitial nephritis (ATIN) and 2346 controls of Chinese ancestry.

TL;DR: Pat et al. as discussed by the authors constructed a consensus mapping between ICD-10 codes and ORPHA codes for rare diseases, then identified individuals with each rare condition in the UK Biobank, and investigated their age at recruitment, sex bias, and comorbidity distributions.

TL;DR: A search-based testing technique that evolves multiple sets of efficient subdomains from which small but effective test suites can be randomly sampled and achieves an average 230% improvement in mutation score over conventional random testing.

TL;DR: In this paper , the authors conducted Mendelian randomization (MR) analysis with six different techniques, using existing GWAS for psoriasis (11,024 cases and 16,336 controls) and MS (14,802 cases and 26,703 controls); they also addressed 10 potential confounding exposures, previously suggested to be associated with both diseases, by including GWAS data from body mass index, coronary artery disease, inflammatory bowel disease, type 1 diabetes (T1D), type 2 diabetes, asthma, rheumatoid arthritis, drinks per week, cigarettes per day, and vitamin D levels.