M
Matthew Patrick
Researcher at University of Michigan
Publications - 68
Citations - 1307
Matthew Patrick is an academic researcher from University of Michigan. The author has contributed to research in topics: Biology & Medicine. The author has an hindex of 14, co-authored 47 publications receiving 661 citations. Previous affiliations of Matthew Patrick include University of Cambridge & University of York.
Papers
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Journal ArticleDOI
IL18-containing 5-gene signature distinguishes histologically identical dermatomyositis and lupus erythematosus skin lesions
Lam C. Tsoi,Mehrnaz Gharaee-Kermani,Celine C. Berthier,Tori Nault,Grace A. Hile,Shannon N. Estadt,Matthew Patrick,Rachael Wasikowski,Allison C. Billi,Lori Lowe,Tamra J. Reed,Johann E. Gudjonsson,J. Michelle Kahlenberg +12 more
TL;DR: A potentially novel molecular signature is identified, with significant clinical implications for differentiating DM from CLE lesions, and the potential role for IL-18 in the pathophysiology of DM skin disease is highlighted.
Journal ArticleDOI
Transcriptomic characterization of prurigo nodularis and the therapeutic response to nemolizumab.
Lam C. Tsoi,Feriel Hacini-Rachinel,Paul Fogel,François Rousseau,Xianying Xing,Matthew Patrick,Allison C. Billi,Celine C. Berthier,J. Michelle Kahlenberg,Anne Lazzari,Henning Wiegmann,Sonja Ständer,Christophe Piketty,Valérie Julia,Jayendra Kumar Krishnaswamy,Johann E. Gudjonsson +15 more
TL;DR: In this paper, the authors provided a comprehensive view of the transcriptomic changes in PN skin and characterized the mechanism of action of the anti-IL-31 receptor inhibitor nemolizumab.
Journal ArticleDOI
Kd-art
Matthew Patrick,Yue Jia +1 more
TL;DR: The trade-off between diversification and intensification to kill mutants is explored to support programs with input parameters that have composite data types (such as arrays and structs) to handle real world non numeric applications.
Proceedings ArticleDOI
MESSI: Mutant Evaluation by Static Semantic Interpretation
TL;DR: This paper proposes a new approach to the mutant reduction problem using static analysis and argues that test suites should be evaluated against those mutants that are harder to kill without being equivalent to the original program.
Journal ArticleDOI
Causal Relationship and Shared Genetic Loci between Psoriasis and Type 2 Diabetes through Trans-Disease Meta-Analysis
Matthew Patrick,Philip E. Stuart,H. Zhang,Qingyuan Zhao,Xianyong Yin,Kevin He,Xu-jie Zhou,Nehal N. Mehta,John J. Voorhees,Michael Boehnke,Johann E. Gudjonsson,Rajan P. Nair,Samuel K. Handelman,James T. Elder,Dajiang J. Liu,Lam C. Tsoi +15 more
TL;DR: In this article, a trans-disease meta-analysis was applied to 8,016,731 well-imputed genetic markers from large-scale meta-analyses of psoriasis (11,024 cases and 16,336 controls) and type 2 diabetes (74,124 cases and 824,006 controls), adjusted for body mass index.