M
Maud Soty
Researcher at French Institute of Health and Medical Research
Publications - 24
Citations - 1838
Maud Soty is an academic researcher from French Institute of Health and Medical Research. The author has contributed to research in topics: Insulin & Insulin resistance. The author has an hindex of 10, co-authored 20 publications receiving 1604 citations. Previous affiliations of Maud Soty include Claude Bernard University Lyon 1 & University of Lyon.
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Journal ArticleDOI
Metformin inhibits hepatic gluconeogenesis in mice independently of the LKB1/AMPK pathway via a decrease in hepatic energy state
Marc Foretz,Sophie Hébrard,Jocelyne Leclerc,Elham Zarrinpashneh,Maud Soty,Gilles Mithieux,Kei Sakamoto,Fabrizio Andreelli,Benoit Viollet +8 more
TL;DR: It is found that in mice lacking AMPK in the liver, blood glucose levels were comparable to those in wild-type mice, and the hypoglycemic effect of metformin was maintained, demonstrating that met formin inhibits hepatic gluconeogenesis in an LKB1- and AMPK-independent manner via a decrease in hepatic energy state.
Journal ArticleDOI
Intestinal Gluconeogenesis Is a Key Factor for Early Metabolic Changes after Gastric Bypass but Not after Gastric Lap-Band in Mice
Stéphanie Troy,Maud Soty,Maud Soty,Lara Ribeiro,Laure Laval,Laure Laval,Stéphanie Migrenne,Xavier Fioramonti,Bruno Pillot,Bruno Pillot,Véronique Fauveau,Roberte Aubert,Benoit Viollet,Benoit Viollet,Marc Foretz,Marc Foretz,Jocelyne Leclerc,Jocelyne Leclerc,A. Duchampt,A. Duchampt,Carine Zitoun,Carine Zitoun,Bernard Thorens,Christophe Magnan,Gilles Mithieux,Gilles Mithieux,Fabrizio Andreelli +26 more
TL;DR: Mechanistic evidence is provided that the beneficial effects of the EGA procedure on food intake and glucose homeostasis involve intestinal gluconeogenesis and its detection via a GLUT-2 and hepatoportal sensor pathway.
Journal ArticleDOI
Gut-Brain Glucose Signaling in Energy Homeostasis
Maud Soty,Maud Soty,Amandine Gautier-Stein,Amandine Gautier-Stein,Fabienne Rajas,Fabienne Rajas,Gilles Mithieux,Gilles Mithieux +7 more
TL;DR: This work raises several questions relating to the conditions under which intestinal gluconeogenesis proceeds and may provide its metabolic benefits and also leads to questions on the advantage conferred by its conservation through a process of natural selection.
Journal ArticleDOI
Protein Feeding Promotes Redistribution of Endogenous Glucose Production to the Kidney and Potentiates Its Suppression by Insulin
TL;DR: It is suggested that a redistribution of glucose production among gluconeogenic organs might occur upon protein feeding, in keeping with the improvement of insulin sensitivity of EGP, most likely involving the hepatic site.
Journal ArticleDOI
A link between hepatic glucose production and peripheral energy metabolism via hepatokines.
Aya Abdul-Wahed,Amandine Gautier-Stein,Amandine Gautier-Stein,Sylvie Casteras,Sylvie Casteras,Maud Soty,Maud Soty,Damien Roussel,Damien Roussel,Caroline Romestaing,Caroline Romestaing,Hervé Guillou,Jean-André Tourette,Jean-André Tourette,Nicolas Pleche,Nicolas Pleche,Carine Zitoun,Carine Zitoun,Blandine Gri,Blandine Gri,Anne Sardella,Anne Sardella,Fabienne Rajas,Fabienne Rajas,Gilles Mithieux,Gilles Mithieux +25 more
TL;DR: It is reported that the specific suppression of hepatic glucose production positively modulates whole-body glucose and energy metabolism during the development of obesity and diabetes.