M
Max F. Perutz
Researcher at Laboratory of Molecular Biology
Publications - 198
Citations - 24791
Max F. Perutz is an academic researcher from Laboratory of Molecular Biology. The author has contributed to research in topics: Hemoglobin & Bohr effect. The author has an hindex of 74, co-authored 198 publications receiving 24297 citations. Previous affiliations of Max F. Perutz include Russian Academy of Sciences & University of York.
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Stereochemistry of cooperative effects in haemoglobin.
TL;DR: The oxygenation of haemoglobin is accompanied by structural changes in the subunits triggered by shifts of the iron atoms relative to the porphyrin and, in the β-subunits, also by the steric effect of oxygen itself.
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Structure of Hæmoglobin: A Three-Dimensional Fourier Synthesis at 5.5-Å. Resolution, Obtained by X-Ray Analysis
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Glutamine repeats as polar zippers: their possible role in inherited neurodegenerative diseases
TL;DR: Molecular modeling followed by optical, electron, and x-ray diffraction studies of a synthetic poly(L-glutamine) shows that it forms beta-sheets strongly held together by hydrogen bonds.
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Three-dimensional Fourier Synthesis of Horse Oxyhaemoglobin at 2.8 Å Resolution: The Atomic Model
TL;DR: The structure of the contacts between unlike subunits suggests that the tetramer, rather than the αβ dimer, is the functional unit of haemoglobin.
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Aromatic rings act as hydrogen bond acceptors
Michael Levitt,Max F. Perutz +1 more
TL;DR: It is of interest that the aromatic hydrogen bond arises from small partial charges centred on the ring carbon and hydrogen atoms: there is no need to consider delocalized electrons.