M
May May Lee
Researcher at Agency for Science, Technology and Research
Publications - 4
Citations - 2540
May May Lee is an academic researcher from Agency for Science, Technology and Research. The author has contributed to research in topics: Mesenchymal stem cell & Population. The author has an hindex of 4, co-authored 4 publications receiving 2176 citations.
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Journal ArticleDOI
Exosome secreted by MSC reduces myocardial ischemia/reperfusion injury.
Ruenn Chai Lai,Fatih Arslan,May May Lee,Newman Siu Kwan Sze,Andre Choo,Tiansheng Chen,Manuel Salto-Tellez,Leo Timmers,Chuen Neng Lee,Reida El Oakley,Gerard Pasterkamp,Dominique P.V. de Kleijn,Sai Kiang Lim +12 more
TL;DR: The novel role of exosomes highlights a new perspective into intercellular mediation of tissue injury and repair, and engenders novel approaches to the development of biologics for tissue repair.
Journal ArticleDOI
Mesenchymal stem cell secretes microparticles enriched in pre-microRNAs
TL;DR: This study suggests that MSCs could facilitate miRNA-mediated intercellular communication by secreting microparticles enriched for pre-miRNA in a high precursor to mature miRNA ratio.
Journal ArticleDOI
Derivation and characterization of human fetal MSCs: An alternative cell source for large-scale production of cardioprotective microparticles
Ruenn Chai Lai,Ruenn Chai Lai,Fatih Arslan,Soon Sim Tan,Betty Tan,Andre Choo,May May Lee,Tiansheng Chen,Bao Ju Teh,John Kun Long Eng,Harwin Sidik,Vivek Tanavde,Wei Sek Hwang,Chuen Neng Lee,Reida El Oakley,Gerard Pasterkamp,Dominique P.V. de Kleijn,Kok Hian Tan,Sai Kiang Lim +18 more
TL;DR: Five MSC cultures from fetal tissue sources were derived and like hESC-derived MSCs; they were highly expandable and had similar telomerase activities and produced secretion that was cardioprotective in a mouse model of MI/R injury.
Journal ArticleDOI
Addendum to “Exosome secreted by MSC reduces myocardial ischemia/reperfusion injury” [Stem Cell Research 4 (2010) 214–222]
Ruenn Chai Lai,Ruenn Chai Lai,Fatih Arslan,May May Lee,Siu Kwan Sze,Andre Choo,Andre Choo,Tiansheng Chen,Manuel Salto-Tellez,Leo Timmers,Chuen Neng Lee,Reida El Oakley,Gerard Pasterkamp,Dominique P.V. de Kleijn,Sai Kiang Lim,Sai Kiang Lim +15 more
TL;DR: This poster presents a probabilistic procedure called a “cell reprograming procedure”, which combines a number of techniques, namely, “s PCR,” “ Bailey’s law” and “tweak” to find the “correct” type of response in the human heart.